Tonka
Well-known member
http://www.pe.terra.com/salud/interna/0,,OI5503667-EI5479,00.html
Spanish to English translation
Children with HIV develop resistance to drugs in Asia
Asia fund scientists found that children from 5 years are developing resistance to drugs for AIDS. The medication needs may be out of reach due to high costs.
Asia Adolescents receiving treatment for HIV are showing early signs of osteoporosis, and children from 5 years are developing resistance to AIDS drugs, said Thursday a group to fight the disease that urged more attention to the issue .
The finding, published the World Day to Combat AIDS, is a reminder that although there are more people in Asia with access to essential medicines against the disease, improved drugs are beyond the scope and patients-adults and children suffer from inadequate care.
In Asia, about 160,000 children are infected with human immunodeficiency virus (HIV) which causes AIDS. Of these, about 57,000 require treatment, but only 30,000 were receiving it in late 2008, according to UNICEF.
TREAT Asia fund scientists found that children from 5 years are developing resistance to drugs for AIDS and may require drugs soon improved, more expensive, they do not have at their disposal.
"In our cohort, 14 percent of children have failed the first line of drugs (...) Some of them already in the second line are less than 5 years," said Annette Sohn, director of TREAT Asia , in a telephone interview.
If the drugs to treat AIDS are not taken when indicated or as often generate resistance. But in Asia, resistance is due to the lack of formulas for children.
"We all made some mistakes on how to manage patients with HIV at the start of the epidemic," said Sohn. "We use adult tablets, we had no pediatric formulations in our countries," he added.
Sohn said that health experts and suppliers of drugs have to find ways to make third-line drugs, more powerful, available to poor children in low income countries.
These drugs are available or are subsidized in rich countries, but are very expensive and sometimes not found in developing nations.
"Unless we generate access to third-line drugs, we're in a clinic with a patient room in which there is nothing to be done and we have no other medicine nung?n to give," said Sohn, a pediatric specialist in children with HIV / AIDS.
A long-term study conducted over 4,000 TREAT HIV patients under 23 years in Asia also showed that a high percentage of adolescents have low bone mineral density, which is a precursor to osteoporosis.
"That's not normal. Children do not have to have low bone mass when they are 16 years and that is why the effect of HIV on their bodies (...) brains, bones and immune system," said Sohn.
The expert considered that this should also have toxic effects that some drugs for AIDS, such as tenofovir, on the bones.
The study covers Thailand, Vietnam, Malaysia, Cambodia, Indonesia and India. TREAT Asia is a network of clinics, hospitals and research institutions working together to improve access to treatment for AIDS.
Spanish to English translation
Children with HIV develop resistance to drugs in Asia
Asia fund scientists found that children from 5 years are developing resistance to drugs for AIDS. The medication needs may be out of reach due to high costs.
Asia Adolescents receiving treatment for HIV are showing early signs of osteoporosis, and children from 5 years are developing resistance to AIDS drugs, said Thursday a group to fight the disease that urged more attention to the issue .
The finding, published the World Day to Combat AIDS, is a reminder that although there are more people in Asia with access to essential medicines against the disease, improved drugs are beyond the scope and patients-adults and children suffer from inadequate care.
In Asia, about 160,000 children are infected with human immunodeficiency virus (HIV) which causes AIDS. Of these, about 57,000 require treatment, but only 30,000 were receiving it in late 2008, according to UNICEF.
TREAT Asia fund scientists found that children from 5 years are developing resistance to drugs for AIDS and may require drugs soon improved, more expensive, they do not have at their disposal.
"In our cohort, 14 percent of children have failed the first line of drugs (...) Some of them already in the second line are less than 5 years," said Annette Sohn, director of TREAT Asia , in a telephone interview.
If the drugs to treat AIDS are not taken when indicated or as often generate resistance. But in Asia, resistance is due to the lack of formulas for children.
"We all made some mistakes on how to manage patients with HIV at the start of the epidemic," said Sohn. "We use adult tablets, we had no pediatric formulations in our countries," he added.
Sohn said that health experts and suppliers of drugs have to find ways to make third-line drugs, more powerful, available to poor children in low income countries.
These drugs are available or are subsidized in rich countries, but are very expensive and sometimes not found in developing nations.
"Unless we generate access to third-line drugs, we're in a clinic with a patient room in which there is nothing to be done and we have no other medicine nung?n to give," said Sohn, a pediatric specialist in children with HIV / AIDS.
A long-term study conducted over 4,000 TREAT HIV patients under 23 years in Asia also showed that a high percentage of adolescents have low bone mineral density, which is a precursor to osteoporosis.
"That's not normal. Children do not have to have low bone mass when they are 16 years and that is why the effect of HIV on their bodies (...) brains, bones and immune system," said Sohn.
The expert considered that this should also have toxic effects that some drugs for AIDS, such as tenofovir, on the bones.
The study covers Thailand, Vietnam, Malaysia, Cambodia, Indonesia and India. TREAT Asia is a network of clinics, hospitals and research institutions working together to improve access to treatment for AIDS.