Chikungunya Outbreaks ? The Globalization of Vectorborne Diseases

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Chikungunya Outbreaks ? The Globalization of Vectorborne Diseases

http://content.nejm.org/cgi/content/extract/356/8/769?ck=nck

R?mi N. Charrel, M.D., Ph.D., Xavier de Lamballerie, M.D., Ph.D., and Didier Raoult, M.D., Ph.D.

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In 2006, an outbreak of chikungunya fever ? an arthralgic<SUP> </SUP>disease caused by a mosquito-borne alphavirus ? swept<SUP> </SUP>over a number of islands in the Indian Ocean (the Comoros, Mauritius,<SUP> </SUP>the Seychelles, Madagascar, Mayotte, and Reunion). In Reunion,<SUP> </SUP>which has a population of 770,000, there were 265,000 clinical<SUP> </SUP>cases (an incidence of 34%), and the disease was implicated<SUP> </SUP>in 237 deaths (about 1 per 1000 clinical cases); a recent report<SUP> </SUP>by Reunion health authorities indicated that the seroprevalence<SUP> </SUP>was 35%, with very few asymptomatic cases. The epidemic had<SUP> </SUP>started with outbreaks in Kenya in 2004 and the Comoros early<SUP> </SUP>in <NOBR>. . .</NOBR> [Full Text of this Article]​

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