tetano
Editor, Senior Moderator
J Virol. 2013 Nov 13. [Epub ahead of print]
Characterization of the non-coding regions of the 1918 influenza A H1N1 virus.
Wang R, Taubenberger JK.
Source
Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA 20892.
Abstract
The terminal non-coding region (NCR) sequences of the eight gene segments of the influenza A/Brevig Mission/1/1918 (H1N1) virus were determined by rapid amplification of cDNA ends (RACE). Chimeric viruses encoding the open reading frames of the 1918 virus but flanked by either the wild-type 1918 NCR sequences, or the NCR sequences of two other H1N1 virus strains, A/WSN/1933 and A/New York/312/2001 were produced. No growth differences between the NCR variant 1918 influenza viruses were noted.
PMID:
24227852
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24227852
Characterization of the non-coding regions of the 1918 influenza A H1N1 virus.
Wang R, Taubenberger JK.
Source
Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA 20892.
Abstract
The terminal non-coding region (NCR) sequences of the eight gene segments of the influenza A/Brevig Mission/1/1918 (H1N1) virus were determined by rapid amplification of cDNA ends (RACE). Chimeric viruses encoding the open reading frames of the 1918 virus but flanked by either the wild-type 1918 NCR sequences, or the NCR sequences of two other H1N1 virus strains, A/WSN/1933 and A/New York/312/2001 were produced. No growth differences between the NCR variant 1918 influenza viruses were noted.
PMID:
24227852
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24227852