tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2017 Aug 9. doi: 10.1111/irv.12469. [Epub ahead of print]
[h=1]Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015.[/h] Nakamura K[SUP]1[/SUP], Shirakura M[SUP]1[/SUP], Fujisaki S[SUP]1[/SUP], Kishida N[SUP]1[/SUP], Burke DF[SUP]2[/SUP], Smith DJ[SUP]2[/SUP], Kuwahara T[SUP]1[/SUP], Takashita E[SUP]1[/SUP], Takayama I[SUP]1[/SUP], Nakauchi M[SUP]1[/SUP], Chadha M[SUP]3[/SUP], Potdar V[SUP]3[/SUP], Bhushan A[SUP]3[/SUP], Upadhyay BP[SUP]4[/SUP], Shakya G[SUP]4[/SUP], Odagiri T[SUP]1[/SUP], Kageyama T[SUP]1[/SUP], Watanabe S[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We characterized influenza A(H1N1)pdm09 isolates from large-scale outbreaks that occurred in Nepal and India in early 2015. Although no specific viral features, which may have caused the outbreaks, were identified, an S84N substitution in hemagglutinin was frequently observed. Chronological phylogenetic analysis revealed that these Nepalese and Indian viruses possessing the S84N substitution constitute potential ancestors of the novel genetic subclade 6B.1 virus that spread globally in the following (2015/16) influenza season. Thus, active surveillance of circulating influenza viruses in the Southern Asia region, including Nepal and India, would be beneficial for detecting novel variant viruses prior to their worldwide spread.
? 2017 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] India; Nepal; influenza A(H1N1)pdm09 virus; outbreak
PMID: 28792671 DOI: 10.1111/irv.12469
Free full text
[h=1]Characterization of influenza A(H1N1)pdm09 viruses isolated from Nepalese and Indian outbreak patients in early 2015.[/h] Nakamura K[SUP]1[/SUP], Shirakura M[SUP]1[/SUP], Fujisaki S[SUP]1[/SUP], Kishida N[SUP]1[/SUP], Burke DF[SUP]2[/SUP], Smith DJ[SUP]2[/SUP], Kuwahara T[SUP]1[/SUP], Takashita E[SUP]1[/SUP], Takayama I[SUP]1[/SUP], Nakauchi M[SUP]1[/SUP], Chadha M[SUP]3[/SUP], Potdar V[SUP]3[/SUP], Bhushan A[SUP]3[/SUP], Upadhyay BP[SUP]4[/SUP], Shakya G[SUP]4[/SUP], Odagiri T[SUP]1[/SUP], Kageyama T[SUP]1[/SUP], Watanabe S[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] We characterized influenza A(H1N1)pdm09 isolates from large-scale outbreaks that occurred in Nepal and India in early 2015. Although no specific viral features, which may have caused the outbreaks, were identified, an S84N substitution in hemagglutinin was frequently observed. Chronological phylogenetic analysis revealed that these Nepalese and Indian viruses possessing the S84N substitution constitute potential ancestors of the novel genetic subclade 6B.1 virus that spread globally in the following (2015/16) influenza season. Thus, active surveillance of circulating influenza viruses in the Southern Asia region, including Nepal and India, would be beneficial for detecting novel variant viruses prior to their worldwide spread.
? 2017 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] India; Nepal; influenza A(H1N1)pdm09 virus; outbreak
PMID: 28792671 DOI: 10.1111/irv.12469
Free full text