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Cell Res. Spiking the MERS-coronavirus receptor.

Giuseppe

Emeritus
[Source: US National Library of Medicine, full page: (LINK). Abstract, edited.]


Cell Res. 2013 Aug 13. doi: 10.1038/cr.2013.108. [Epub ahead of print]

Spiking the MERS-coronavirus receptor.

Bosch BJ, Raj VS, Haagmans BL.

Source: Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine, Utrecht University, 3508 TD Utrecht, the Netherlands.


Abstract

A novel coronavirus, the Middle East respiratory syndrome coronavirus, recently emerged through zoonotic transmission, causing a severe lower respiratory tract infection in humans. In two recent papers, one published in Cell Research, the crystal structure of the viral receptor-binding domain in complex with the host CD26/dipeptidyl peptidase 4 receptor has now been characterized.


PMID: 23938293 [PubMed - as supplied by publisher]


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