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CDC swine flu powerpoints from late June 2009
- Thread starter Zac
- Start date
Re: CDC swine flu powerpoints from late June 2009
Some highlights:
Secondary attack rate in household contacts:
? Acute respiratory illness: 19%
? Influenza-like illness: 8-12%
? Higher attack rates observed in schools
? Serial interval:
? Acute respiratory illness: 2.0-3.1 days
? Influenza-like illness: 2.4-3.1 days
---
(Rapid flu test) Antigen detection misses many infections
? Rapid diagnostic tests: Sensitivity: 10-51%
? Immunoflourescene: Sensitivity: 47%
---
Hospitalized Pandemic H1N1 Cases, U.S.
(N = 268)
? Median time from onset to admission
? 3 days (range 1-14 days)
? Median length of stay
? 3 days (range 1-59)
? Median age
? 22 years (range 21 days-86 years)
? 128 female (48%), 140 male (52%)
71% with underlying co-morbidities
21% admitted to ICU
13% required mechanical ventilation
17 deaths (6.3%)
---
Rapid progression of pneumonia
Suggests viral infection of lower respiratory tract
? Possible high viral replication triggering
cytokine dysregulation (similar to highly pathogenic
avian influenza H5N1 virus infection?)
? Acute lung injury, rapid progression to ARDS
Refractory ARDS observed
Some highlights:
Secondary attack rate in household contacts:
? Acute respiratory illness: 19%
? Influenza-like illness: 8-12%
? Higher attack rates observed in schools
? Serial interval:
? Acute respiratory illness: 2.0-3.1 days
? Influenza-like illness: 2.4-3.1 days
---
(Rapid flu test) Antigen detection misses many infections
? Rapid diagnostic tests: Sensitivity: 10-51%
? Immunoflourescene: Sensitivity: 47%
---
Hospitalized Pandemic H1N1 Cases, U.S.
(N = 268)
? Median time from onset to admission
? 3 days (range 1-14 days)
? Median length of stay
? 3 days (range 1-59)
? Median age
? 22 years (range 21 days-86 years)
? 128 female (48%), 140 male (52%)
71% with underlying co-morbidities
21% admitted to ICU
13% required mechanical ventilation
17 deaths (6.3%)
---
Rapid progression of pneumonia
Suggests viral infection of lower respiratory tract
? Possible high viral replication triggering
cytokine dysregulation (similar to highly pathogenic
avian influenza H5N1 virus infection?)
? Acute lung injury, rapid progression to ARDS
Refractory ARDS observed
somebodyoutthere
Well-known member
Re: CDC swine flu powerpoints from late June 2009
Why the asterisk next to the "Fever" symptom again? It seems to always have an asterisk with no corresponding footnote. I would appreciate enlightenment if anyone knows.
Why the asterisk next to the "Fever" symptom again? It seems to always have an asterisk with no corresponding footnote. I would appreciate enlightenment if anyone knows.
