tetano
Editor, Senior Moderator
Case Rep Pediatr
. 2022 Nov 23;2022:3811170.
doi: 10.1155/2022/3811170. eCollection 2022.
Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
Kristie Searcy[SUP] 1 [/SUP], Apoorva Jagadish[SUP] 2 [/SUP], Patricia Pichilingue-Reto[SUP] 3 [/SUP], Radhakrishna Baliga[SUP] 4 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia, and end organ damage. This is present in severe cases of COVID-19 and in hemolytic uremic syndrome (HUS) commonly caused by Escherichia coli (E.coli) 0157:H7. We report a novel case of a toddler who presented with classic features suggestive of HUS characterized by bloody diarrhea followed by thrombocytopenia, hemolytic anemia, and acute kidney injury, in whom a polymerase chain reaction (PCR) test for SARS-CoV-2 was positive.
. 2022 Nov 23;2022:3811170.
doi: 10.1155/2022/3811170. eCollection 2022.
Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
Kristie Searcy[SUP] 1 [/SUP], Apoorva Jagadish[SUP] 2 [/SUP], Patricia Pichilingue-Reto[SUP] 3 [/SUP], Radhakrishna Baliga[SUP] 4 [/SUP]
Affiliations
- PMID: 36466432
- PMCID: PMC9711990
- DOI: 10.1155/2022/3811170
Abstract
Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia, and end organ damage. This is present in severe cases of COVID-19 and in hemolytic uremic syndrome (HUS) commonly caused by Escherichia coli (E.coli) 0157:H7. We report a novel case of a toddler who presented with classic features suggestive of HUS characterized by bloody diarrhea followed by thrombocytopenia, hemolytic anemia, and acute kidney injury, in whom a polymerase chain reaction (PCR) test for SARS-CoV-2 was positive.