tetano
Editor, Senior Moderator
Case Rep Neurol Med
. 2025 May 5:2025:8840308.
doi: 10.1155/crnm/8840308. eCollection 2025. Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
Emily Grew[SUP] 1 [/SUP], Garrett Gianneschi[SUP] 2 [/SUP], Janet Elgallab[SUP] 2 [/SUP]
Affiliations
Chronic inflammatory demyelinating polyneuropathy (CIDP) following viral infections and influenza vaccination has been well documented. However, there have been no confirmed natural influenza A infections leading to development of CIDP. Therefore, we present the case of a 6-year-old male who developed CIDP following a confirmed influenza A infection. Initially presenting with typical flu-like symptoms, the patient experienced a gradual onset of gait instability and leg weakness approximately 1 month later. Despite initial improvement with intravenous immunoglobulin therapy following a diagnosis of Guillain-Barré syndrome, his symptoms relapsed, including lower extremity weakness, incontinence, and sensory loss. Electromyography confirmed a demyelinating polyneuropathy, leading to a diagnosis of CIDP.
. 2025 May 5:2025:8840308.
doi: 10.1155/crnm/8840308. eCollection 2025. Chronic Inflammatory Demyelinating Polyneuropathy Following Natural Influenza A Infection in a Pediatric Patient: A Case Report and Literature Review
Emily Grew[SUP] 1 [/SUP], Garrett Gianneschi[SUP] 2 [/SUP], Janet Elgallab[SUP] 2 [/SUP]
Affiliations
- PMID: 40365113
- PMCID: PMC12069850
- DOI: 10.1155/crnm/8840308
Chronic inflammatory demyelinating polyneuropathy (CIDP) following viral infections and influenza vaccination has been well documented. However, there have been no confirmed natural influenza A infections leading to development of CIDP. Therefore, we present the case of a 6-year-old male who developed CIDP following a confirmed influenza A infection. Initially presenting with typical flu-like symptoms, the patient experienced a gradual onset of gait instability and leg weakness approximately 1 month later. Despite initial improvement with intravenous immunoglobulin therapy following a diagnosis of Guillain-Barré syndrome, his symptoms relapsed, including lower extremity weakness, incontinence, and sensory loss. Electromyography confirmed a demyelinating polyneuropathy, leading to a diagnosis of CIDP.