tetano
Editor, Senior Moderator
Case Rep Crit Care
. 2020 Oct 17;2020:8876932.
doi: 10.1155/2020/8876932. eCollection 2020.
COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
Habiba Hussain[SUP] 1 [/SUP], Matthew Sehring[SUP] 2 [/SUP], Bhagat Singh Aulakh[SUP] 2 [/SUP]
Affiliations
Abstract
The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay.
. 2020 Oct 17;2020:8876932.
doi: 10.1155/2020/8876932. eCollection 2020.
COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
Habiba Hussain[SUP] 1 [/SUP], Matthew Sehring[SUP] 2 [/SUP], Bhagat Singh Aulakh[SUP] 2 [/SUP]
Affiliations
- PMID: 33101734
- PMCID: PMC7573660
- DOI: 10.1155/2020/8876932
Abstract
The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay.