tetano
Editor, Senior Moderator
Cardiol J
. 2022 Mar 4.
doi: 10.5603/CJ.a2022.0009. Online ahead of print.
Elevated resting heart rate as independent in-hospital prognostic marker in COVID-19
Jennifer Vanoli[SUP] 1 [/SUP], Giacomo Marro[SUP] 2 [/SUP], Raffaella Dell'Oro[SUP] 1 [/SUP], Rita Facchetti[SUP] 1 [/SUP], Fosca Quarti-Trevano[SUP] 1 [/SUP], Domenico Spaziani[SUP] 3 [/SUP], Guido Grassi[SUP] 4 [/SUP]
Affiliations
Abstract
Background: Scarce and non-homogeneous data are available on the prognostic value of clinic heart rate in coronavirus disease 2019 (COVID-19).
Methods: The present study evaluated in 389 patients hospitalized for COVID-19 disease the in-hospital prognostic value of resting heart rate (HR), assessed over different time periods, i.e., at hospital admission, during initial 3 days and 7 days of hospitalization.
Results: Results show that assessment of this hemodynamic variable during hospitalization provides information on the clinical outcome of the patients, greater HR values being associated with a worse in-hospital prognosis. The prognostic value of elevated HR during COVID-19: 1) was independent on other confounders such as age, gender, comorbidities and fever, 2) appeared to be strengthened by repeated measurements of HR during the initial 3/7 days of hospitalization and 3) was detectable in patients in which the therapeutic intervention did not include drugs, such as beta-blockers, calcium antagonists, digoxin, ivabradine and antiarrhythmic compounds known to interfere with HR.
Conclusions: Heart rate may represent an important marker of a patient's outcome in COVID-19 disease.
Keywords: coronavirus disease 2019 (COVID-19); heart rate; prognosis; sympathetic nervous system.
. 2022 Mar 4.
doi: 10.5603/CJ.a2022.0009. Online ahead of print.
Elevated resting heart rate as independent in-hospital prognostic marker in COVID-19
Jennifer Vanoli[SUP] 1 [/SUP], Giacomo Marro[SUP] 2 [/SUP], Raffaella Dell'Oro[SUP] 1 [/SUP], Rita Facchetti[SUP] 1 [/SUP], Fosca Quarti-Trevano[SUP] 1 [/SUP], Domenico Spaziani[SUP] 3 [/SUP], Guido Grassi[SUP] 4 [/SUP]
Affiliations
- PMID: 35244197
- DOI: 10.5603/CJ.a2022.0009
Abstract
Background: Scarce and non-homogeneous data are available on the prognostic value of clinic heart rate in coronavirus disease 2019 (COVID-19).
Methods: The present study evaluated in 389 patients hospitalized for COVID-19 disease the in-hospital prognostic value of resting heart rate (HR), assessed over different time periods, i.e., at hospital admission, during initial 3 days and 7 days of hospitalization.
Results: Results show that assessment of this hemodynamic variable during hospitalization provides information on the clinical outcome of the patients, greater HR values being associated with a worse in-hospital prognosis. The prognostic value of elevated HR during COVID-19: 1) was independent on other confounders such as age, gender, comorbidities and fever, 2) appeared to be strengthened by repeated measurements of HR during the initial 3/7 days of hospitalization and 3) was detectable in patients in which the therapeutic intervention did not include drugs, such as beta-blockers, calcium antagonists, digoxin, ivabradine and antiarrhythmic compounds known to interfere with HR.
Conclusions: Heart rate may represent an important marker of a patient's outcome in COVID-19 disease.
Keywords: coronavirus disease 2019 (COVID-19); heart rate; prognosis; sympathetic nervous system.