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Canine Influenza Virus A(H3N2) Clade with Antigenic Variation, China, 2016-2017

tetano

Editor, Senior Moderator
Emerg Infect Dis. 2019 Jan 17;25(1). doi: 10.3201/eid2501.171878. [Epub ahead of print]
[h=1]Canine Influenza Virus A(H3N2) Clade with Antigenic Variation, China, 2016-2017.[/h] Lyu Y, Song S, Zhou L, Bing G, Wang Q, Sun H, Chen M, Hu J, Wang M, Sun H, Pu J, Xia Z, Liu J, Sun Y.
[h=3]Abstract[/h] During 2012-2017, we collected throat swabs from dogs in China to characterize canine influenza virus (CIV) A(H3N2) isolates. A new antigenically and genetically distinct CIV H3N2 clade possessing mutations associated with mammalian adaptation emerged in 2016 and replaced previously circulating strains. This clade probably poses a risk for zoonotic infection.


[h=4]KEYWORDS:[/h] China; H3N2; PB2; adaptation; antigenicity; canine influenza; dogs; evolution; influenza; influenza A virus; mammalian adaptations; respiratory infections; serology; surveillance; viruses; zoonoses

PMID: 30407904 DOI: 10.3201/eid2501.171878
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