JimO
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Source: http://www.cdph.ca.gov/programs/vrdl/Documents/FluUpdate11.07.09.pdf
CALIFORNIA 2009 H1N1 INFLUENZA UPDATE
Highlights:
? In California, 2009 H1N1 influenza continues to be widespread. While most indicators are showing sustained high levels of illness, some indicators suggest that illness may be leveling off; however, this can change at any time. Reported cases of new hospitalizations have leveled off somewhat from last week. As in previous weeks, the rate of hospitalizations remains highest among children under one year of age. Reported fatalities among all age groups rose from 17 cases last week to 31 this week, likely reflecting the expected delay in reporting of fatalities relative to reporting of hospitalizations. There was also a considerable increase in reported severe pediatric illness, including fatalities, this week. Outpatient ILI illness continues to be well above expected levels for this time of year; however, the percent of visits for ILI appears to be leveling off or declining somewhat. Additionally, influenza A detections at sentinel laboratories have declined in recent weeks. As with national data, almost all influenza viruses detected over the last week continue to be 2009 H1N1.
? Local health departments have been reporting hospitalized 2009 H1N1 influenza cases as weekly aggregate numbers since August 12, 2009. From November 1 ? November 7, 2009, 560 hospitalized/fatal cases were reported; there have been 5,380 hospitalizations and/or fatalities, with 1,034 cases requiring intensive care, reported to date.
? The statewide incidence rate of reported 2009 H1N1 influenza hospitalizations and fatalities is 13.9 per 100,000 population.
? CDPH received 31 reports of fatal 2009 H1N1 influenza cases for the week ending on November 7, 2009; a total of 297 2009 H1N1 influenza deaths have been reported to CDPH to date.
? A total of 1,914 hospitalized or fatal 2009 H1N1 influenza cases in pediatric patients 18 years or younger, including 33 deaths, have been reported to CDPH to date.
? Fifty-three new cases meeting the case definition for severe pediatric influenza were reported this week, including 4 fatalities. Forty-nine of the cases are confirmed/probable 2009 H1N1 influenza; additional testing is pending for the remaining four cases.
? The aggregate numbers of hospitalized or fatal cases reported to CDPH this week included 43 pregnant 2009 H1N1 influenza cases; a total of 419 pregnant hospitalized or fatal cases, including 11 deaths (case-fatality ratio 2.6%), have been reported to CDPH to date.
? In recent weeks, almost all influenza A-positive specimens tested by PCR at VRDL and by the Respiratory Laboratory Network have been subsequently confirmed as 2009 H1N1 influenza, reflecting that the predominant circulating influenza strain in California remains 2009 H1N1 influenza.
? Three cases of oseltamivir resistance have been identified in California residents with laboratory-confirmed 2009 H1N1 influenza infections. One case was initially identified at VRDL; the other two were initially confirmed by outside laboratories. To date, of 1204 specimens tested at VRDL, all but two have tested negative for the H275Y resistance mutation.
? At this time, the data indicate that prevalence of oseltamivir-resistant 2009 H1N1 influenza is quite limited. On September 22, 2009, the CDC released updated interim recommendations for the use of antiviral medications in the treatment and prevention of influenza. These recommendations are available at: http://www.cdc.gov/h1n1flu/recommendations.htm.
? Outbreaks continue to be reported. In the last several weeks, the greatest number of outbreaks of respiratory diseases has been reported from schools.
CALIFORNIA 2009 H1N1 INFLUENZA UPDATE
Highlights:
? In California, 2009 H1N1 influenza continues to be widespread. While most indicators are showing sustained high levels of illness, some indicators suggest that illness may be leveling off; however, this can change at any time. Reported cases of new hospitalizations have leveled off somewhat from last week. As in previous weeks, the rate of hospitalizations remains highest among children under one year of age. Reported fatalities among all age groups rose from 17 cases last week to 31 this week, likely reflecting the expected delay in reporting of fatalities relative to reporting of hospitalizations. There was also a considerable increase in reported severe pediatric illness, including fatalities, this week. Outpatient ILI illness continues to be well above expected levels for this time of year; however, the percent of visits for ILI appears to be leveling off or declining somewhat. Additionally, influenza A detections at sentinel laboratories have declined in recent weeks. As with national data, almost all influenza viruses detected over the last week continue to be 2009 H1N1.
? Local health departments have been reporting hospitalized 2009 H1N1 influenza cases as weekly aggregate numbers since August 12, 2009. From November 1 ? November 7, 2009, 560 hospitalized/fatal cases were reported; there have been 5,380 hospitalizations and/or fatalities, with 1,034 cases requiring intensive care, reported to date.
? The statewide incidence rate of reported 2009 H1N1 influenza hospitalizations and fatalities is 13.9 per 100,000 population.
? CDPH received 31 reports of fatal 2009 H1N1 influenza cases for the week ending on November 7, 2009; a total of 297 2009 H1N1 influenza deaths have been reported to CDPH to date.
? A total of 1,914 hospitalized or fatal 2009 H1N1 influenza cases in pediatric patients 18 years or younger, including 33 deaths, have been reported to CDPH to date.
? Fifty-three new cases meeting the case definition for severe pediatric influenza were reported this week, including 4 fatalities. Forty-nine of the cases are confirmed/probable 2009 H1N1 influenza; additional testing is pending for the remaining four cases.
? The aggregate numbers of hospitalized or fatal cases reported to CDPH this week included 43 pregnant 2009 H1N1 influenza cases; a total of 419 pregnant hospitalized or fatal cases, including 11 deaths (case-fatality ratio 2.6%), have been reported to CDPH to date.
? In recent weeks, almost all influenza A-positive specimens tested by PCR at VRDL and by the Respiratory Laboratory Network have been subsequently confirmed as 2009 H1N1 influenza, reflecting that the predominant circulating influenza strain in California remains 2009 H1N1 influenza.
? Three cases of oseltamivir resistance have been identified in California residents with laboratory-confirmed 2009 H1N1 influenza infections. One case was initially identified at VRDL; the other two were initially confirmed by outside laboratories. To date, of 1204 specimens tested at VRDL, all but two have tested negative for the H275Y resistance mutation.
? At this time, the data indicate that prevalence of oseltamivir-resistant 2009 H1N1 influenza is quite limited. On September 22, 2009, the CDC released updated interim recommendations for the use of antiviral medications in the treatment and prevention of influenza. These recommendations are available at: http://www.cdc.gov/h1n1flu/recommendations.htm.
? Outbreaks continue to be reported. In the last several weeks, the greatest number of outbreaks of respiratory diseases has been reported from schools.