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California 2011-2012 Flu Season: FINAL REPORT

M

Missouriwatcher

Editor, Senior Moderator
Weeks 40 & 41: Low Activity
Influenza A (2009 H1), A (H3), and B have all been identified in the first two weeks of this influenza season. Of 810 specimens tested by the RLN and sentinel labs during Weeks 40 and 41, 8 (1.0%) were positive for influenza A and 1 (0.1%) was influenza B. Most of the positive results have been reported from Southern California.

The California Department of Public Health Viral and Rickettsial Disease Laboratory (CDPH-VRDL) has not tested any specimens for antiviral resistance to date. No California specimens have been strain typed by the Centers for Disease Control and Prevention (CDC) to date.

CDPH has received no reports of laboratory-confirmed influenza-associated deaths among patients under 65 years of age.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-42 (Sporadic)

Re: California 2011-2012 Flu Season: Weeks 40-42 (Sporadic)

Week 42: Sporadic

In Week 42, outpatient influenza-like illness (ILI) activity as a percentage of total visits to sentinel providers was low (1.2%).
Of 590 specimens tested by the Respiratory Laboratory Network (RLN) and sentinel laboratories during Week 42, 4 (0.7%) were positive for influenza A; all were from northern California.
No California specimens have been strain typed by the federal Centers for Disease Control and Prevention (CDC) to date.
In week 42, CDPH received no reports of laboratory-confirmed influenza-associated deaths among patients under 65 years of age.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-43 (Sporadic)

Re: California 2011-2012 Flu Season: Weeks 40-43 (Sporadic)

Week 43: Sporadic
Outpatient influenza-like illness (ILI) activity as a percentage of total visits to sentinel providers was low (0.9%).
Of 562 specimens tested by the Respiratory Laboratory Network (RLN) and sentinel laboratories during Week 43, 2 (0.4%) were positive for influenza A.
The California Department of Public Health Viral and Rickettsial Disease Laboratory (CDPH-VRDL) has not tested any specimens for antiviral resistance to date.
No California specimens have been strain typed by the federal Centers for Disease Control and Prevention (CDC) to date.
CDPH has received no reports of laboratory-confirmed influenza-associated deaths among persons less than 65 years of age.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-44 (Sporadic)

Re: California 2011-2012 Flu Season: Weeks 40-44 (Sporadic)

Week 44: Sporadic
Outpatient influenza-like illness (ILI) activity as a percentage of total visits to sentinel providers was low (1.2%).
Of 640 specimens tested by the Respiratory Laboratory Network (RLN) and sentinel laboratories during Week 44, 3 (0.5%) were positive for influenza A and 3 (0.5%) were positive for influenza B.
The California Department of Public Health Viral and Rickettsial Disease Laboratory (CDPH-VRDL) has not tested any specimens for antiviral resistance to date.
No California specimens have been strain-typed to date.
CDPH has received no reports of laboratory-confirmed influenza-associated deaths among persons less than 65 years of age.

During Week 44, the percentage of Kaiser hospitalizations for P&I increased in southern California (3.9%, compared to 3.2% in Week 43) and northern California (4.5%, compared to 4.1% in Week 43).
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-47 (Sporadic)

Re: California 2011-2012 Flu Season: Weeks 40-47 (Sporadic)

Weeks 46, 47: Sporadic
Outpatient influenza-like illness (ILI) activity as a percentage of total visits to sentinel providers was low for Weeks 46 (1.4%) and 47 (1.4%).

Of 1788 specimens tested by the Respiratory Laboratory Network (RLN) and sentinel laboratories during Weeks 46 and 47, 9 (0.5%) were positive for influenza A and 5 (0.3%) were positive for influenza B.

No California specimens have been strain-typed to date.

CDPH has received no reports of laboratory-confirmed influenza-associated deaths among persons less than 65 years of age.

There were no reports of acute respiratory outbreaks due to laboratory-confirmed influenza in Weeks 46 and 47.

The percentages of Kaiser hospitalizations for P&I in northern California were similar in Weeks 46 (4.7%) and 47 (5.2%) compared to Week 45 (5.0%). In Southern California, the percentages of Kaiser hospitalizations for P&I increased in Weeks 46 (4.4%) and 47 (4.9%) compared to Week 45 (3.6%)
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-48 (Sporadic)

Re: California 2011-2012 Flu Season: Weeks 40-48 (Sporadic)

Week 48: Sporadic
Circulation of a novel swine-origin triple reassortant H3N2 influenza (S-OtrH3N2) virus has been reported in four states, including Pennsylvania, Indiana, Maine, and Iowa. Of the ten reported cases, all except one have been children; two had underlying chronic medical illness and were briefly hospitalized. While almost all have had either direct or indirect exposure to swine, investigation of a recently reported influenza-like illness (ILI) cluster of three children in Iowa has suggested limited person-to-person transmission.

All of the cases were identified by routine influenza surveillance and testing at a state public health laboratory. In California, the Respiratory Laboratory Network (RLN) provides the state’s front-line for testing for influenza. All RLN laboratories are able to screen for the S-OtrH3N2 influenza virus; to date, the S-OtrH3N2 virus has not been identified in California, but testing has been limited due to the low number of influenza specimens submitted to RLN laboratories. RLN laboratories are encouraged to work with the California Department of Public Health Viral and Rickettsial Disease Laboratory (CDPH-VRDL) and their local partners to perform broad influenza testing in different populations to monitor for the emergence of the S-OtrH3N2 virus in California.

Influenza activity remains low in California.
Outpatient ILI activity as a percentage of total visits to sentinel providers was low (1.1%).
Of 1,012 specimens tested by the RLN and sentinel laboratories during Week 48, 4 (0.4%) were positive for influenza B and 8 (0.8%) were positive for influenza A; 1 (12.5%) influenza A specimen was subtyped as A (H3).
The CDPH-VRDL has not tested any specimens for antiviral resistance to date.
One specimen from a California resident has been strain-typed as A/Perth/16/2009-like, the influenza A (H3N2) component of the 2011-12 influenza vaccine for the Northern Hemisphere.
CDPH has received no reports of laboratory-confirmed influenza-associated deaths among persons less than 65 years of age.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-49 (Sporadic)

Re: California 2011-2012 Flu Season: Weeks 40-49 (Sporadic)

Week 49: Sporadic
Influenza activity remains low in California.
Outpatient ILI activity as a percentage of total visits to sentinel providers was low (1.0%).
Of 940 specimens tested by the RLN and sentinel laboratories during Week 49, 4 (0.4%) were positive for influenza B and 7 (0.7%) were positive for influenza A; 3 (42.9%) influenza A specimens were subtyped as seasonal A (H3) and 4 (57.1%) were not subtyped.
The CDPH-VRDL has performed antiviral resistance testing on eight influenza specimens during the 2011-2012 influenza season; no resistance to neuraminidase inhibitors has been identified.
One specimen from a California resident has been strain-typed as A/Perth/16/2009-like, the influenza A (H3N2) component of the 2011-12 influenza vaccine for the Northern Hemisphere.
CDPH has received no reports of laboratory-confirmed influenza-associated deaths among persons less than 65 years of age.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-50 (One Death Reported)

Re: California 2011-2012 Flu Season: Weeks 40-50 (One Death Reported)

Week 50: Sporadic
1 death reported (under 65 years); total 1

Influenza activity remains low in California.
ILI: 2.0%
During Week 50, the percentage of Kaiser hospitalizations for P&I decreased in northern California (5.3%, compared to 6.0% in Week 49), and increased in southern California (4.6%, compared to 3.9% in Week 49).

Of 956 specimens tested by the Respiratory Laboratory Network (RLN) and sentinel laboratories during Week 50, 4 (0.4%) were positive for influenza B and 15 (1.6%) were positive for influenza A; no further subtyping was performed.
Three specimens from California residents have been strain-typed this season; all matched with components of the 2011-12 influenza vaccine for the Northern Hemisphere.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx

County of San Diego surveillance
http://www.sdcounty.ca.gov/hhsa/programs/phs/community_epidemiology/disease_surveillance.html
 
Re: California 2011-2012 Flu Season: Weeks 40-52 (No New Deaths; Total One)

Re: California 2011-2012 Flu Season: Weeks 40-52 (No New Deaths; Total One)

Weeks 51 and 52:
Influenza activity remains low in California.
Outpatient ILI activity as a percentage of total visits to sentinel providers was low in Weeks 51 (1.1%) and 52 (1.2%).

Of 2620 specimens tested by the Respiratory Laboratory Network (RLN) and sentinel laboratories during Weeks 51 and 52, 15 (0.6%) were positive for influenza B and 66 (2.5%) were positive for influenza A; of the influenza A specimens, 14 (21.2%) were subtyped as A (H3), 2 (3.0%) were subtyped as A (2009 H1N1), and 50 (75.8%) were not subtyped.

The California Department of Public Health Viral and Rickettsial Disease Laboratory (CDPH-VRDL) has performed antiviral resistance testing on 20 influenza specimens during the 2011-2012 influenza season; no resistance to neuraminidase inhibitors has been identified.

Three specimens from California residents have been strain-typed this season; all matched with components of the 2011-12 influenza vaccine for the Northern Hemisphere.

CDPH received no report of a laboratory-confirmed influenza-associated death among persons less than 65 years of age in Weeks 51 and 52.

No suspected or confirmed influenza A (H3N2)v [variant influenza A (H3N2), formerly called swine-origin triple reassortant A (H3N2)] has been detected in California to date.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-1 (One New Death; Total Two)

Re: California 2011-2012 Flu Season: Weeks 40-1 (One New Death; Total Two)

Week 1:
1 new death (age 50-60 years); total 2
ILI: 1.6%

5.5% positive for influenza (majority A)
The California Department of Public Health Viral and Rickettsial Disease Laboratory (CDPH-VRDL) has performed antiviral resistance testing on 20 influenza specimens during the 2011-2012 influenza season; no resistance to neuraminidase inhibitors has been identified.

Fourteen specimens from California residents have been strain-typed this season; all but one matched with components of the 2011-12 influenza vaccine for the Northern Hemisphere.

No suspected or confirmed influenza A (H3N2)v [variant influenza A (H3N2), formerly called swine-origin triple reassortant A (H3N2)] has been detected in California to date.

The proportion of human metapneumovirus (hMPV) detections continued to increase in Week 1 (6.8%, compared to 5.3%, 5.2%, and 2.1% in Weeks 52, 51, and 50, respectively). Likewise, respiratory syncytial virus (RSV) detections increased to 11.3% in Week 1 compared to 9.8% and 6.1% in Weeks 52 and 51, respectively.

CDPH received one report of a laboratory-confirmed influenza outbreak at a skilled nursing facility in the San Francisco Bay Area region. A total of 4 residents were ill; 3 were confirmed positive for influenza B by PCR (1), culture (1) and rapid test (1). No hospitalizations or deaths occurred.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-2 (One Pediatric Death; Total Three Deaths)

Re: California 2011-2012 Flu Season: Weeks 40-2 (One Pediatric Death; Total Three Deaths)

Week 2: Local
1 pediatric death (age 10-14); total three deaths, two being adults

Outpatient influenza-like illness (ILI) activity as a percentage of total visits to sentinel providers remained low in Week 2 (1.2%).

Of 1299 specimens tested by the Respiratory Laboratory Network (RLN) and sentinel laboratories during Week 2, 77 (5.9%) were positive for influenza; of these 12 (15.6%) were influenza B and 65 (84.4%) were influenza A. Of the 65 specimens that tested positive for influenza A, 17 (26.2%) were subtyped as seasonal A (H3), 8 (12.3%) were subtyped as 2009 A (H1), and 40 (61.5%) were not subtyped.

The California Department of Public Health Viral and Rickettsial Disease Laboratory (CDPH-VRDL) has performed antiviral resistance testing on 20 influenza specimens during the 2011-2012 influenza season; no resistance to neuraminidase inhibitors has been identified.

Fourteen specimens from California residents have been strain-typed this season; all but one matched with components of the 2011-12 influenza vaccine for the Northern Hemisphere.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx

NOTE: To date during the 2011-2012 influenza season, CDPH has received three reports of influenza-associated deaths, including this child and two adults in the 30-49 year age group with chronic medical conditions.
 
Re: California 2011-2012 Flu Season: Weeks 40-4 (No New Deaths; Total Three)

Re: California 2011-2012 Flu Season: Weeks 40-4 (No New Deaths; Total Three)

Week 4: Regional
No new deaths; total 3
ILI: 2%
11.7% positive for influenza (A, A/H3, 2009 A/H1, B)
Twenty-seven specimens from California residents have been strain-typed this season; all but four influenza B strains match the 2011-12 influenza vaccine.

CDPH received two reports of laboratory-confirmed influenza outbreaks, both at skilled nursing facilities, in the San Francisco bay area region in Week 4. One was associated with influenza B and the other was associated with influenza A with pending subtyping.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx

San Diego County Health Dept
Number of detections on the rise
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-5 (Two New Deaths; Total Five)

Re: California 2011-2012 Flu Season: Weeks 40-5 (Two New Deaths; Total Five)

Week 5: Widespread
2 new deaths (30-49 and 50-64 years of age); total 5

Outpatient influenza-like illness (ILI) remained low in Week 5 (2.5%).

Of 1889 specimens tested during Week 5, 270 (14.3%) were positive for influenza; of these 26 (9.6%) were influenza B and 244 (90.4%) were influenza A.
38 (15.6%) were subtyped as seasonal A (H3),
17 (7.0%) were subtyped as 2009 A (H1), and
189 (77.5%) were not subtyped.

No resistance to neuraminidase inhibitors has been identified in 28 influenza isolates tested during the 2011-2012 influenza season.

Twenty-seven specimens from California residents have been strain-typed this season; all but four influenza B strains match the 2011-12 influenza vaccine.

CDPH received two reports of laboratory-confirmed influenza outbreaks in the southern California region. One was at a skilled nursing facility and it was associated with influenza A and the other was at a state prison and was associated with A (2009 H1N1).
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-6 (No New Deaths; Total Five)

Re: California 2011-2012 Flu Season: Weeks 40-6 (No New Deaths; Total Five)

Week 6: Widespread
No new deaths; total 5
ILI: 3.2%
15.2% positive for influenza

No resistance to neuraminidase inhibitors has been identified in 39 influenza isolates tested during the 2011-2012 influenza season.
Twenty-seven specimens from California residents have been strain-typed this season; all but four influenza B strains match the 2011-12 influenza vaccine.
No laboratory-confirmed influenza-associated deaths among persons less than 65 years were reported in week 6.
No suspected or confirmed influenza A (H3N2)v [variant influenza A (H3N2), formerly called swine-origin triple reassortant A (H3N2)] have been detected in California.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-7 (One New Death; Total Six)

Re: California 2011-2012 Flu Season: Weeks 40-7 (One New Death; Total Six)

Week 7:
1 new death; total 6 CDPH received one report of an influenza-associated death due to influenza A (H3) in a child in the 0-4 year age-group from the northern California region in week 7. To date during the 2011-2012 influenza season, CDPH has received six reports of influenza-associated deaths among cases less than 65 years old; two were among children 0-17 years and four were among adults 18-64 years.

Outpatient influenza-like illness (ILI) is down 1.3% in Week 7 (2.3%) compared to Week 6 (3.6%).

16.6% positive for influenza; of these 24 (6.4%) were influenza B and 353 (93.6%) were influenza A, 58 (16.4%) were subtyped as seasonal A (H3), 48 (13.6%) were subtyped as 2009 A (H1), and 247 (70.0%) were not subtyped.

No resistance to neuraminidase inhibitors has been identified in 44 influenza isolates tested during the 2011-2012 influenza season.

Twenty-seven specimens from California residents have been strain-typed this season; all but four influenza B strains match the 2011-12 influenza vaccine.

CDPH received two reports of laboratory-confirmed influenza outbreaks in Week 7. One was at a correctional facility in the San Francisco bay area region and was associated with influenza A (2009 H1N1) and the other was at a school in the central region and was associated with influenza A.
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-8 (No New Deaths; Total Six)

Re: California 2011-2012 Flu Season: Weeks 40-8 (No New Deaths; Total Six)

Week 8: Widespread
No new deaths; total 6

Outpatient influenza-like illness (ILI) was up 0.4% in Week 8 (2.3%)compared to Week 7 (1.9%).
Of 2287 specimens tested during Week 8, 467 (20.4%) were positive for influenza.
No resistance to neuraminidase inhibitors has been identified in 44 influenza isolates tested during the 2011-2012 influenza season.
Forty-five specimens from California residents have been strain-typed this season; all but four influenza B strains match the 2011-12 influenza vaccine.
No laboratory-confirmed influenza-associated deaths among persons less than 65 years was reported in week 8.
No suspected or confirmed influenza A (H3N2)v [variant influenza A (H3N2), formerly called swine-origin triple reassortant A (H3N2)] have been detected in California.

CDPH received three reports of laboratory-confirmed influenza outbreaks in week 8; one at a congregate living facility in the central region that was associated with influenza A (H3) and one each at a congregate living facility and school in the San Francisco bay area region that were associated with influenza A (no subtyping performed).
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
Re: California 2011-2012 Flu Season: Weeks 40-9 (Three New Deaths; Total Nine)

Re: California 2011-2012 Flu Season: Weeks 40-9 (Three New Deaths; Total Nine)

Week 9: Widespread
3 new deaths (ages 36-64) To date during the 2011-2012 influenza season, CDPH has received nine reports of influenza-associated deaths among persons less than 65 years old; two were among children 0-17 years and seven were among adults 18-64 years.

Outpatient influenza-like illness (ILI) was down 0.4% in week 9 (1.9%) compared to week 8 (2.3%).
Of 2206 specimens tested during week 9, 467 (21.2%) were positive for influenza; of these
42 (9.0%) were influenza B and
425 (91.0%) were influenza A.
92 (21.6%) were subtyped as seasonal A (H3),
54 (12.7%) were subtyped as 2009 A (H1), and
279 (65.6%) were not subtyped.
No resistance to neuraminidase inhibitors has been identified in 44 influenza isolates tested during the 2011-2012 influenza season.
Forty-five specimens from California residents have been strain-typed this season; all but four influenza B strains match the 2011-12 influenza vaccine.

CDPH received three reports of laboratory-confirmed influenza outbreaks in week 9; one at a congregate living facility in the southern region that was associated with influenza A (no subtyping), one at a jail in the southern region that was associated with influenza A (2009 H1N1) and one at a school in the San Francisco bay area region that was associated with influenza A (H3).
http://www.cdph.ca.gov/HealthInfo/discond/Pages/Influenza(Flu).aspx
 
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