tetano
Editor, Senior Moderator
Braz J Infect Dis
. 2020 Sep 15;S1413-8670(20)30139-2.
doi: 10.1016/j.bjid.2020.08.011. Online ahead of print.
SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
Amanda Mandarino Alves[SUP] 1 [/SUP], Erika Yuki Yvamoto[SUP] 2 [/SUP], Maira Andrade Nacimbem Marzinotto[SUP] 2 [/SUP], Ana Cristina de S? Teixeira[SUP] 2 [/SUP], Flair Jos? Carrilho[SUP] 2 [/SUP]
Affiliations
Abstract
During SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. Angiotensin-converting enzyme-2, the functional virus host cell receptor expressed by organs and tissues, seems to have an important role in the pathophysiology and presentation of this disease. In pancreas, this receptor is expressed in both exocrine glands and islets, being a potential target for the virus and subsequent pancreatic injury. There are few articles reporting pancreatic injury in COVID-19 patients but most of them do not report acute pancreatitis. Diagnosing acute pancreatitis secondary to SARS-CoV-2 infection is challenging due to the need to rule out other etiologies as well the notable heterogeneous presentations. Herein we report the case of a patient with COVID-19 who developed severe acute pancreatitis.
Keywords: Acute pancreatitis; COVID-19; SARS-CoV-2.
. 2020 Sep 15;S1413-8670(20)30139-2.
doi: 10.1016/j.bjid.2020.08.011. Online ahead of print.
SARS-CoV-2 leading to acute pancreatitis: an unusual presentation
Amanda Mandarino Alves[SUP] 1 [/SUP], Erika Yuki Yvamoto[SUP] 2 [/SUP], Maira Andrade Nacimbem Marzinotto[SUP] 2 [/SUP], Ana Cristina de S? Teixeira[SUP] 2 [/SUP], Flair Jos? Carrilho[SUP] 2 [/SUP]
Affiliations
- PMID: 32961108
- DOI: 10.1016/j.bjid.2020.08.011
Abstract
During SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. Angiotensin-converting enzyme-2, the functional virus host cell receptor expressed by organs and tissues, seems to have an important role in the pathophysiology and presentation of this disease. In pancreas, this receptor is expressed in both exocrine glands and islets, being a potential target for the virus and subsequent pancreatic injury. There are few articles reporting pancreatic injury in COVID-19 patients but most of them do not report acute pancreatitis. Diagnosing acute pancreatitis secondary to SARS-CoV-2 infection is challenging due to the need to rule out other etiologies as well the notable heterogeneous presentations. Herein we report the case of a patient with COVID-19 who developed severe acute pancreatitis.
Keywords: Acute pancreatitis; COVID-19; SARS-CoV-2.