tetano
Editor, Senior Moderator
Brain Sci
. 2022 Apr 26;12(5):556.
doi: 10.3390/brainsci12050556.
Potential Factors That Contribute to Post-COVID-19 Fatigue in Women
Thorsten Rudroff[SUP] 1 2 [/SUP], Craig D Workman[SUP] 1 [/SUP], Andrew D Bryant[SUP] 3 [/SUP]
Affiliations
Abstract
Mortality of acute coronavirus disease (COVID-19) is higher in men than in women. On the contrary, women experience more long-term consequences of the disease, such as fatigue. In this perspective article, we proposed a model of the potential factors that might contribute to the higher incidence of post-COVID-19 fatigue in women. Specifically, psycho-physiological factors are features that might increase central factors (e.g., inflammation) and result in greater perceptions of fatigue. Furthermore, pre-existing conditions likely play a prominent role. This model offers a framework for researchers and clinicians, and future research is required to validate our proposed model and elucidate all mechanisms of the increased incidence and prevalence of post-COVID-19 fatigue in women.
Keywords: fatigue; inflammation; post-COVID 19; sex differences.
. 2022 Apr 26;12(5):556.
doi: 10.3390/brainsci12050556.
Potential Factors That Contribute to Post-COVID-19 Fatigue in Women
Thorsten Rudroff[SUP] 1 2 [/SUP], Craig D Workman[SUP] 1 [/SUP], Andrew D Bryant[SUP] 3 [/SUP]
Affiliations
- PMID: 35624943
- DOI: 10.3390/brainsci12050556
Abstract
Mortality of acute coronavirus disease (COVID-19) is higher in men than in women. On the contrary, women experience more long-term consequences of the disease, such as fatigue. In this perspective article, we proposed a model of the potential factors that might contribute to the higher incidence of post-COVID-19 fatigue in women. Specifically, psycho-physiological factors are features that might increase central factors (e.g., inflammation) and result in greater perceptions of fatigue. Furthermore, pre-existing conditions likely play a prominent role. This model offers a framework for researchers and clinicians, and future research is required to validate our proposed model and elucidate all mechanisms of the increased incidence and prevalence of post-COVID-19 fatigue in women.
Keywords: fatigue; inflammation; post-COVID 19; sex differences.