tetano
Editor, Senior Moderator
Brain Hemorrhages
. 2022 Aug 12.
doi: 10.1016/j.hest.2022.08.002. Online ahead of print.
Intracerebral Hemorrhage associated COVID-19 patient with normal coagulation profile after ECMO treatment: A case report"
Wael Osman[SUP] 1 2 [/SUP], Hussein Awad El Gharieb[SUP] 1 2 [/SUP], Hossam Ibrahim[SUP] 3 [/SUP], Ahmed Alanazi[SUP] 4 [/SUP], Mostafa Meshref[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Coronavirus disease 2019 (COVID-19) is a novel coronavirus-caused infectious acute respiratory disease that can progress to severe acute respiratory distress syndrome (ARDS). For severe cases, extracorporeal membrane oxygenation (ECMO) is an excellent treatment option. ECMO had a number of side effects, including bleeding. Intracerebral hemorrhage can occur in COVID patients due to a variety of mechanisms, including covid's effect on ACE-2 receptors and subsequent hypertension, coagulopathy, DIC, or medication, such as anticoagulant use.
Case: We present a case of a 53-year-old male COVID-19 patient who developed multiple, massive, severe intracerebral hemorrhages (ICH) despite a normal coagulation profile after ECMO treatment.
Conclusion: COVID-19 can progress to severe acute respiratory distress syndrome (ARDS), necessitating the use of extracorporeal membrane oxygenation (ECMO). Although ICH is not a common complication in patients with COVID-19 disease, it is unknown why this patient had a lower threshold of ICH despite having a normal coagulation profile.
Keywords: Coronavirus; ICH; extracorporeal membrane oxygenation (ECMO).
. 2022 Aug 12.
doi: 10.1016/j.hest.2022.08.002. Online ahead of print.
Intracerebral Hemorrhage associated COVID-19 patient with normal coagulation profile after ECMO treatment: A case report"
Wael Osman[SUP] 1 2 [/SUP], Hussein Awad El Gharieb[SUP] 1 2 [/SUP], Hossam Ibrahim[SUP] 3 [/SUP], Ahmed Alanazi[SUP] 4 [/SUP], Mostafa Meshref[SUP] 1 [/SUP]
Affiliations
- PMID: 35975277
- PMCID: PMC9373471
- DOI: 10.1016/j.hest.2022.08.002
Abstract
Background: Coronavirus disease 2019 (COVID-19) is a novel coronavirus-caused infectious acute respiratory disease that can progress to severe acute respiratory distress syndrome (ARDS). For severe cases, extracorporeal membrane oxygenation (ECMO) is an excellent treatment option. ECMO had a number of side effects, including bleeding. Intracerebral hemorrhage can occur in COVID patients due to a variety of mechanisms, including covid's effect on ACE-2 receptors and subsequent hypertension, coagulopathy, DIC, or medication, such as anticoagulant use.
Case: We present a case of a 53-year-old male COVID-19 patient who developed multiple, massive, severe intracerebral hemorrhages (ICH) despite a normal coagulation profile after ECMO treatment.
Conclusion: COVID-19 can progress to severe acute respiratory distress syndrome (ARDS), necessitating the use of extracorporeal membrane oxygenation (ECMO). Although ICH is not a common complication in patients with COVID-19 disease, it is unknown why this patient had a lower threshold of ICH despite having a normal coagulation profile.
Keywords: Coronavirus; ICH; extracorporeal membrane oxygenation (ECMO).