Br J Haematol . Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukaemia

[tetano]

Br J Haematol


. 2023 Jul 9.
doi: 10.1111/bjh.18911. Online ahead of print. Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukaemia

Milica Miladinovic[SUP] 1 2 3 [/SUP], Jan-Henning Klusmann[SUP] 1 2 3 [/SUP]



Affiliations

• PMID: 37423608
• DOI: 10.1111/bjh.18911

Abstract

You et al. present an extraordinary case of a refractory acute myeloid leukaemia (AML) patient who achieved long-term complete remission after infection with Influenza A. Using mouse models, the researchers examined the underlying immunological mechanisms and discovered a decrease in leukaemia proliferation and improved survival in Influenza-A virus-infected mice. These results indicate the potential therapeutic relevance of Influenza A in the treatment of haematological cancers. Commentary on: You et al. Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukemia. Br J Haematol 2023 (Online ahead of print). doi: 10.1111/bjh.18876.

Keywords: acute myeloid leukemia; influenza A virus; long-term remission.

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