Br J Haematol . Effect of low or high doses of low-molecular-weight heparin on thrombin generation and other haemostasis parameters in critically il

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Br J Haematol


. 2020 Jul 6;10.1111/bjh.17003.
doi: 10.1111/bjh.17003. Online ahead of print.
Effect of low or high doses of low-molecular-weight heparin on thrombin generation and other haemostasis parameters in critically ill patients with COVID-19


Antonio Chistolini[SUP] 1 [/SUP], Franco Ruberto[SUP] 2 [/SUP], Francesco Alessandri[SUP] 2 [/SUP], Cristina Santoro[SUP] 1 [/SUP], Francesco Barone[SUP] 1 [/SUP], Maria Cristina Puzzolo[SUP] 1 [/SUP], Giancarlo Ceccarelli[SUP] 3 [/SUP], Maria L De Luca[SUP] 1 [/SUP], Massimo Mancone[SUP] 4 [/SUP], Domenico Alvaro[SUP] 5 [/SUP], Fabio M Pulcinelli[SUP] 6 [/SUP], Maurizio Martelli[SUP] 1 [/SUP], Robin Fo?[SUP] 1 [/SUP], Francesco Pugliese[SUP] 2 [/SUP], Policlinico Umberto I COVID‐19 Group



Collaborators, Affiliations

• PMID: 32779783
• PMCID: PMC7361613
• DOI: 10.1111/bjh.17003

Abstract

The clinical picture of the coronavirus 2 (SARS‐CoV‐2)/COVID‐19‐related acute respiratory syndrome is often associated with a coagulopathy. An elevated D‐dimer has been linked with an unfavorable prognosis in COVID‐19 patients.

Keywords: COVID‐19; low‐molecular‐weight heparin; thrombin generation assay