tetano
Editor, Senior Moderator
BMJ Open. 2018 Feb 15;8(2):e018709. doi: 10.1136/bmjopen-2017-018709.
[h=1]Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey.[/h] Chen L[SUP]1,[/SUP][SUP]2[/SUP], Zhou F[SUP]1[/SUP], Li H[SUP]3[/SUP], Xing X[SUP]4[/SUP], Han X[SUP]5[/SUP], Wang Y[SUP]3[/SUP], Zhang C[SUP]6[/SUP], Suo L[SUP]7[/SUP], Wang J[SUP]8[/SUP], Yu G[SUP]9[/SUP], Wang G[SUP]10[/SUP], Yao X[SUP]11[/SUP], Yu H[SUP]12[/SUP], Wang L[SUP]13[/SUP], Liu M[SUP]1[/SUP], Xue C[SUP]1[/SUP], Liu B[SUP]7[/SUP], Zhu X[SUP]14[/SUP], Li Y[SUP]1[/SUP], Xiao Y[SUP]1[/SUP], Cui X[SUP]3[/SUP], Li L[SUP]3[/SUP], Uyeki TM[SUP]15[/SUP], Wang C[SUP]3,[/SUP][SUP]16[/SUP], Cao B[SUP]3,[/SUP][SUP]16[/SUP]; CAP-China network.
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVES:[/h] To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China.
[h=4]DESIGN:[/h] This was a multicentre, retrospective, observational study.
[h=4]SETTING:[/h] 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 PARTICIPANTS: Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms.
[h=4]PRIMARY AND SECONDARY OUTCOME MEASURES:[/h] Resource use for CAP management.
[h=4]RESULTS:[/h] Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0-1 and Pneumonia Severity Index risk class I-II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%.
[h=4]CONCLUSIONS:[/h] These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China.
[h=4]TRIAL REGISTRATION NUMBER:[/h] NCT02489578; Results.
? Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
[h=4]KEYWORDS:[/h] China; community-acquired pneumonia; disease characteristics; management
PMID: 29449294 DOI: 10.1136/bmjopen-2017-018709
[h=1]Disease characteristics and management of hospitalised adolescents and adults with community-acquired pneumonia in China: a retrospective multicentre survey.[/h] Chen L[SUP]1,[/SUP][SUP]2[/SUP], Zhou F[SUP]1[/SUP], Li H[SUP]3[/SUP], Xing X[SUP]4[/SUP], Han X[SUP]5[/SUP], Wang Y[SUP]3[/SUP], Zhang C[SUP]6[/SUP], Suo L[SUP]7[/SUP], Wang J[SUP]8[/SUP], Yu G[SUP]9[/SUP], Wang G[SUP]10[/SUP], Yao X[SUP]11[/SUP], Yu H[SUP]12[/SUP], Wang L[SUP]13[/SUP], Liu M[SUP]1[/SUP], Xue C[SUP]1[/SUP], Liu B[SUP]7[/SUP], Zhu X[SUP]14[/SUP], Li Y[SUP]1[/SUP], Xiao Y[SUP]1[/SUP], Cui X[SUP]3[/SUP], Li L[SUP]3[/SUP], Uyeki TM[SUP]15[/SUP], Wang C[SUP]3,[/SUP][SUP]16[/SUP], Cao B[SUP]3,[/SUP][SUP]16[/SUP]; CAP-China network.
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVES:[/h] To describe the clinical characteristics and management of patients hospitalised with community-acquired pneumonia (CAP) in China.
[h=4]DESIGN:[/h] This was a multicentre, retrospective, observational study.
[h=4]SETTING:[/h] 13 teaching hospitals in northern, central and southern China from 1 January 2014 to 31 December 2014 PARTICIPANTS: Information on hospitalised patients aged ≥14 years with radiographically confirmed pneumonia with illness onset in the community was collected using standard case report forms.
[h=4]PRIMARY AND SECONDARY OUTCOME MEASURES:[/h] Resource use for CAP management.
[h=4]RESULTS:[/h] Of 14 793 patients screened, 5828 with radiographically confirmed CAP were included in the final analysis. Low mortality risk patients with a CURB-65 score 0-1 and Pneumonia Severity Index risk class I-II accounted for 81.2% (4434/5594) and 56.4% (2034/3609) patients, respectively. 21.7% (1111/5130) patients had already achieved clinical stability on admission. A definite or probable pathogen was identified only in 12.7% (738/5828) patients. 40.9% (1575/3852) patients without pseudomonal infection risk factors received antimicrobial overtreatment regimens. The median duration between clinical stability to discharge was 5.0 days with 30-day mortality of 4.2%.
[h=4]CONCLUSIONS:[/h] These data demonstrated the overuse of health resources in CAP management, indicating that there is potential for improvement and substantial savings to healthcare systems in China.
[h=4]TRIAL REGISTRATION NUMBER:[/h] NCT02489578; Results.
? Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
[h=4]KEYWORDS:[/h] China; community-acquired pneumonia; disease characteristics; management
PMID: 29449294 DOI: 10.1136/bmjopen-2017-018709