tetano
Editor, Senior Moderator
BMC Pulm Med
. 2025 Apr 8;25(1):163.
doi: 10.1186/s12890-025-03613-0. A comparison of pulmonary function pre and post mild SARS-CoV-2 infection among healthy adults
Raz Roje Taib[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Yuval Kozlov[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Aya Ekshtein[SUP] 1 2 [/SUP], Barak Gordon[SUP] 1 2 3 [/SUP], Ori Wand[SUP] #[/SUP][SUP] 4 5 6 [/SUP], Oded Ben-Ari[SUP] #[/SUP][SUP] 1 2 3 7 [/SUP]
Affiliations
Background: SARS-CoV-2 infection frequently involves the respiratory system and may impact on pulmonary function tests (PFT) of recovered individuals. Studies which compare post-COVID-19 PFT to pre-illness measurements are scarce. The primary objective of this study was to assess the effect of COVID-19 on PFT soon after infection.
Methods: In this prospective observational study, PFT were measured early following recovery from COVID-19 among healthy military aircrew. Spirometry values were compared to pre-COVID-19 measurements, and abnormality rates of lung volumes and diffusion capacity for carbon monoxide (DLCO) were assessed.
Results: The study included 252 aviators, 97.6% males, mean age 34.9-years, following recovery from SARS-CoV-2 infection. Participants manifested mild symptoms (79.4%) or were asymptomatic (20.6%). Post-COVID-19 spirometry results 10.79 ± 5.67 days following infection were compared to measurements performed 41.3 ± 28.59 months earlier. Pre- and post-COVID-19 results were comparable, with similar minimal abnormalities rates (2% and 4.4%, respectively). In addition, there were no restrictive abnormalities following infection, and just 7.7% of individuals had a marginally low DLCO of 70-80% of predicted.
Conclusion: Among vaccinated, healthy adults, mild COVID-19 had no significant impact on PFT early post-infection. The data suggest that systematic PFT testing might not be necessary for asymptomatic healthy individuals who recovered from mild COVID-19.
Keywords: Aviation medicine; COVID-19; Coronavirus disease; Pulmonary function test; Reduced oxygen breathing device; SARS-CoV-2.
. 2025 Apr 8;25(1):163.
doi: 10.1186/s12890-025-03613-0. A comparison of pulmonary function pre and post mild SARS-CoV-2 infection among healthy adults
Raz Roje Taib[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Yuval Kozlov[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Aya Ekshtein[SUP] 1 2 [/SUP], Barak Gordon[SUP] 1 2 3 [/SUP], Ori Wand[SUP] #[/SUP][SUP] 4 5 6 [/SUP], Oded Ben-Ari[SUP] #[/SUP][SUP] 1 2 3 7 [/SUP]
Affiliations
- PMID: 40200177
- PMCID: PMC11980318
- DOI: 10.1186/s12890-025-03613-0
Background: SARS-CoV-2 infection frequently involves the respiratory system and may impact on pulmonary function tests (PFT) of recovered individuals. Studies which compare post-COVID-19 PFT to pre-illness measurements are scarce. The primary objective of this study was to assess the effect of COVID-19 on PFT soon after infection.
Methods: In this prospective observational study, PFT were measured early following recovery from COVID-19 among healthy military aircrew. Spirometry values were compared to pre-COVID-19 measurements, and abnormality rates of lung volumes and diffusion capacity for carbon monoxide (DLCO) were assessed.
Results: The study included 252 aviators, 97.6% males, mean age 34.9-years, following recovery from SARS-CoV-2 infection. Participants manifested mild symptoms (79.4%) or were asymptomatic (20.6%). Post-COVID-19 spirometry results 10.79 ± 5.67 days following infection were compared to measurements performed 41.3 ± 28.59 months earlier. Pre- and post-COVID-19 results were comparable, with similar minimal abnormalities rates (2% and 4.4%, respectively). In addition, there were no restrictive abnormalities following infection, and just 7.7% of individuals had a marginally low DLCO of 70-80% of predicted.
Conclusion: Among vaccinated, healthy adults, mild COVID-19 had no significant impact on PFT early post-infection. The data suggest that systematic PFT testing might not be necessary for asymptomatic healthy individuals who recovered from mild COVID-19.
Keywords: Aviation medicine; COVID-19; Coronavirus disease; Pulmonary function test; Reduced oxygen breathing device; SARS-CoV-2.