Giuseppe
Emeritus
[Source: BMC, Gut Pathogens, full text: (LINK). Abstract, edited.]
Prevalence of aac(6')-Ib-cr plasmid-mediated and chromosome-encoded fluoroquinolone resistance in Enterobacteriaceae in Italy
Ilaria Frasson, Antonietta Cavallaro, Cristina Bergo, Sara N Richter and Giorgio Palu
Gut Pathogens 2011, 3:12 doi:10.1186/1757-4749-3-12
Published: 9 August 2011
Abstract (provisional)
The spread of aac(6')-Ib-cr plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The aac(6')-Ib-cr gene was found exclusively in Escherichia coli strains. The gene was located on a plasmid which presented additional ESBL genes. Most of the clinical strains were clonally related and displayed three point mutations at the topoisomerase level which conferred high resistance to fluoroquinolones.
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Prevalence of aac(6')-Ib-cr plasmid-mediated and chromosome-encoded fluoroquinolone resistance in Enterobacteriaceae in Italy
Ilaria Frasson, Antonietta Cavallaro, Cristina Bergo, Sara N Richter and Giorgio Palu
Gut Pathogens 2011, 3:12 doi:10.1186/1757-4749-3-12
Published: 9 August 2011
Abstract (provisional)
The spread of aac(6')-Ib-cr plasmid-mediated quinolone resistance determinants was evaluated in 197 enterobacterial isolates recovered in an Italian teaching hospital. The aac(6')-Ib-cr gene was found exclusively in Escherichia coli strains. The gene was located on a plasmid which presented additional ESBL genes. Most of the clinical strains were clonally related and displayed three point mutations at the topoisomerase level which conferred high resistance to fluoroquinolones.
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