tetano
Editor, Senior Moderator
BMC Infect Dis
. 2021 May 21;21(1):465.
doi: 10.1186/s12879-021-06143-2.
Symptomatic sinus bradycardia due to electrolyte imbalances in syndrome of inappropriate antidiuretic hormone (SIADH) related covid-19: a case report
Muzakkir Amir[SUP] 1 2 [/SUP], Andi Renata[SUP] 3 4 [/SUP], Levina Tri Ratana[SUP] 3 4 [/SUP]
Affiliations
Abstract
Background: Coronavirus Disease-2019 (COVID-19) has been declared a global pandemic since March 11th, 2020. Despite emerging reports and literature covering a broad spectrum of COVID-19 clinical manifestations, facets of COVID-19 have not been fully elucidated. To the authors' concern, sinus bradycardia as a manifestation of COVID-19-induced syndrome of inappropriate antidiuretic hormone (SIADH) has never been reported before.
Case presentation: In this paper, we report a case of a 59-year-old male patient with confirmed COVID-19 initially presented with presyncope. Further investigations reveal sinus bradycardia related to COVID-19-induced SIADH. This case highlights the possibility of immuno-neuroendocrino-cardiovascular crosstalk resulting in an atypical manifestation of COVID-19: near syncope due to sinus bradycardia.
Conclusions: Another possible cause of sinus bradycardia in COVID-19 is electrolyte imbalance due to COVID-19-related SIADH.
Keywords: COVID-19; Electrolyte imbalances; SIADH; Symptomatic sinus bradycardia.
. 2021 May 21;21(1):465.
doi: 10.1186/s12879-021-06143-2.
Symptomatic sinus bradycardia due to electrolyte imbalances in syndrome of inappropriate antidiuretic hormone (SIADH) related covid-19: a case report
Muzakkir Amir[SUP] 1 2 [/SUP], Andi Renata[SUP] 3 4 [/SUP], Levina Tri Ratana[SUP] 3 4 [/SUP]
Affiliations
- PMID: 34020617
- DOI: 10.1186/s12879-021-06143-2
Abstract
Background: Coronavirus Disease-2019 (COVID-19) has been declared a global pandemic since March 11th, 2020. Despite emerging reports and literature covering a broad spectrum of COVID-19 clinical manifestations, facets of COVID-19 have not been fully elucidated. To the authors' concern, sinus bradycardia as a manifestation of COVID-19-induced syndrome of inappropriate antidiuretic hormone (SIADH) has never been reported before.
Case presentation: In this paper, we report a case of a 59-year-old male patient with confirmed COVID-19 initially presented with presyncope. Further investigations reveal sinus bradycardia related to COVID-19-induced SIADH. This case highlights the possibility of immuno-neuroendocrino-cardiovascular crosstalk resulting in an atypical manifestation of COVID-19: near syncope due to sinus bradycardia.
Conclusions: Another possible cause of sinus bradycardia in COVID-19 is electrolyte imbalance due to COVID-19-related SIADH.
Keywords: COVID-19; Electrolyte imbalances; SIADH; Symptomatic sinus bradycardia.