tetano
Editor, Senior Moderator
BMC Infect Dis
. 2023 Nov 6;23(1):763.
doi: 10.1186/s12879-023-08769-w. Association between ozone and influenza transmissibility in China
Jiao Yang[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Ting Zhang[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Liuyang Yang[SUP] #[/SUP][SUP] 1 2 3 4 [/SUP], Xuan Han[SUP] 1 2 3 [/SUP], Xingxing Zhang[SUP] 1 2 3 [/SUP], Qing Wang[SUP] 1 2 3 [/SUP], Luzhao Feng[SUP] 5 6 7 [/SUP], Weizhong Yang[SUP] 8 9 10 [/SUP]
Affiliations
Background: Common air pollutants such as ozone (O[SUB]3[/SUB]), sulfur dioxide (SO[SUB]2[/SUB]), nitrogen dioxide (NO[SUB]2[/SUB]), and particulate matter play significant roles as influential factors in influenza-like illness (ILI). However, evidence regarding the impact of O[SUB]3[/SUB] on influenza transmissibility in multi-subtropical regions is limited, and our understanding of the effects of O[SUB]3[/SUB] on influenza transmissibility in temperate regions remain unknown.
Methods: We studied the transmissibility of influenza in eight provinces across both temperate and subtropical regions in China based on 2013 to 2018 provincial-level surveillance data on influenza-like illness (ILI) incidence and viral activity. We estimated influenza transmissibility by using the instantaneous reproduction number ([Formula: see text]) and examined the relationships between transmissibility and daily O[SUB]3[/SUB] concentrations, air temperature, humidity, and school holidays. We developed a multivariable regression model for [Formula: see text] to quantify the contribution of O[SUB]3[/SUB] to variations in transmissibility.
Results: Our findings revealed a significant association between O[SUB]3[/SUB] and influenza transmissibility. In Beijing, Tianjin, Shanghai and Jiangsu, the association exhibited a U-shaped trend. In Liaoning, Gansu, Hunan, and Guangdong, the association was L-shaped. When aggregating data across all eight provinces, a U-shaped association was emerged. O[SUB]3[/SUB] was able to accounted for up to 13% of the variance in [Formula: see text]. O[SUB]3[/SUB] plus other environmental drivers including mean daily temperature, relative humidity, absolute humidity, and school holidays explained up to 20% of the variance in [Formula: see text].
Conclusions: O[SUB]3[/SUB] was a significant driver of influenza transmissibility, and the association between O[SUB]3[/SUB] and influenza transmissibility tended to display a U-shaped pattern.
Keywords: Flu; Influenza; Ozone; Transmissibility.
. 2023 Nov 6;23(1):763.
doi: 10.1186/s12879-023-08769-w. Association between ozone and influenza transmissibility in China
Jiao Yang[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Ting Zhang[SUP] #[/SUP][SUP] 1 2 3 [/SUP], Liuyang Yang[SUP] #[/SUP][SUP] 1 2 3 4 [/SUP], Xuan Han[SUP] 1 2 3 [/SUP], Xingxing Zhang[SUP] 1 2 3 [/SUP], Qing Wang[SUP] 1 2 3 [/SUP], Luzhao Feng[SUP] 5 6 7 [/SUP], Weizhong Yang[SUP] 8 9 10 [/SUP]
Affiliations
- PMID: 37932657
- PMCID: PMC10626750
- DOI: 10.1186/s12879-023-08769-w
Background: Common air pollutants such as ozone (O[SUB]3[/SUB]), sulfur dioxide (SO[SUB]2[/SUB]), nitrogen dioxide (NO[SUB]2[/SUB]), and particulate matter play significant roles as influential factors in influenza-like illness (ILI). However, evidence regarding the impact of O[SUB]3[/SUB] on influenza transmissibility in multi-subtropical regions is limited, and our understanding of the effects of O[SUB]3[/SUB] on influenza transmissibility in temperate regions remain unknown.
Methods: We studied the transmissibility of influenza in eight provinces across both temperate and subtropical regions in China based on 2013 to 2018 provincial-level surveillance data on influenza-like illness (ILI) incidence and viral activity. We estimated influenza transmissibility by using the instantaneous reproduction number ([Formula: see text]) and examined the relationships between transmissibility and daily O[SUB]3[/SUB] concentrations, air temperature, humidity, and school holidays. We developed a multivariable regression model for [Formula: see text] to quantify the contribution of O[SUB]3[/SUB] to variations in transmissibility.
Results: Our findings revealed a significant association between O[SUB]3[/SUB] and influenza transmissibility. In Beijing, Tianjin, Shanghai and Jiangsu, the association exhibited a U-shaped trend. In Liaoning, Gansu, Hunan, and Guangdong, the association was L-shaped. When aggregating data across all eight provinces, a U-shaped association was emerged. O[SUB]3[/SUB] was able to accounted for up to 13% of the variance in [Formula: see text]. O[SUB]3[/SUB] plus other environmental drivers including mean daily temperature, relative humidity, absolute humidity, and school holidays explained up to 20% of the variance in [Formula: see text].
Conclusions: O[SUB]3[/SUB] was a significant driver of influenza transmissibility, and the association between O[SUB]3[/SUB] and influenza transmissibility tended to display a U-shaped pattern.
Keywords: Flu; Influenza; Ozone; Transmissibility.