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Blood Coagul Fibrinolysis . The association of oxygen saturation, tomography findings and D-dimer levels in coronavirus disease 2019 patients

tetano

Editor, Senior Moderator
Blood Coagul Fibrinolysis


. 2020 Dec;31(8):558-561.
doi: 10.1097/MBC.0000000000000964.
The association of oxygen saturation, tomography findings and D-dimer levels in coronavirus disease 2019 patients


Kadir S Yal?in[SUP] 1 [/SUP], Benan Kasapoğlu, Recep Alanli, Murat B K???kay, Ali Koşar



Affiliations

Abstract

: Coronavirus disease is a highly contagious disease caused by systemic acute respiratory syndrome coronavirus 2 with high mortality rates. We aimed to evaluate the relationship between serum D-dimer levels and tomography findings at the time of admission in patients diagnosed with coronavirus disease 2019 (COVID-19). This study included 94 patients, 48 women (51%) and 46 men (49%), diagnosed by PCR method. Patients without any suspicious findings on thorax tomography and having oxygen saturation above 90% at the time of presentation were included as the first group. Patients with suspicious tomography findings but having oxygen saturation above 90% were designed as the second group, and patients with both suspicious tomography findings for COVID-19 and low oxygen saturation levels (<90%) at the time of admission were taken as the third group. Patients with oxygen desaturation were significantly older than the patients with normal oxygen saturations (P = 0.001). Patients with thorax tomography findings were having significantly higher D-dimer levels (P = 0.001). Patients with oxygen desaturation were having significantly higher D-dimer levels than the patients with normal oxygen saturations (P = 0.001). There was a significant negative correlation between oxygen saturation and D-dimer levels in all patients with and without tomography findings (r = -0.301, P = 0.016). Similarly, there was a significant positive correlation between the oxygen saturation and the lymphocyte count (r = 0.300, P < 0.017). Thorax tomography and D-dimer levels significantly correlate in patients with suspected COVID-19 admission. It should be kept in mind that patients with low oxygen saturation and high D-dimer levels may have serious lung involvement.
 
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