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Unexpected Detection of Highly Pathogenic Avian Influenza (HPAI) H5N1 virus in bovine Semen
View ORCID ProfileAilam Lim, Keith Poulsen, Leonardo C Caserta, Lizheng Guan, Eryn Opgernorth, Maxwell Beal, Amie J. Eisfeld, Yoshihiro Kawaoka, View ORCID ProfileDiego Diel
doi: https://doi.org/10.1101/2025.10.16.682947
This article is a preprint and has not been certified by peer review [what does this mean?].
Abstract
Since March 2024, HPAI H5N1 virus has infected dairy cattle in the U.S., prompting concern about novel transmission routes. During an outbreak in California, HPAI H5N1 RNA was detected in an asymptomatic bull's semen. Although infectious virus was not isolated, questions remain about semen-associated transmission risks and biosecurity practices.
https://www.biorxiv.org/content/10.1101/2025.10.16.682947v1
Unexpected Detection of Highly Pathogenic Avian Influenza (HPAI) H5N1 virus in bovine Semen
View ORCID ProfileAilam Lim, Keith Poulsen, Leonardo C Caserta, Lizheng Guan, Eryn Opgernorth, Maxwell Beal, Amie J. Eisfeld, Yoshihiro Kawaoka, View ORCID ProfileDiego Diel
doi: https://doi.org/10.1101/2025.10.16.682947
This article is a preprint and has not been certified by peer review [what does this mean?].
Abstract
Since March 2024, HPAI H5N1 virus has infected dairy cattle in the U.S., prompting concern about novel transmission routes. During an outbreak in California, HPAI H5N1 RNA was detected in an asymptomatic bull's semen. Although infectious virus was not isolated, questions remain about semen-associated transmission risks and biosecurity practices.
https://www.biorxiv.org/content/10.1101/2025.10.16.682947v1