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BA.5.5 sublineage with S:N450D (105 seq. mostly US as of 2022-07-25) - GitHub

Mary Wilson

Well-known member
agamedilab opened this issue Jul 25, 2022

Proposal for a sublineage of BA.5.5
Earliest sequence: 04.06.2022 (USA)
Countries detected: mostly USA, UK, Israel, Germany, Mexico, Austria

Defining mutation:
A22910G = S:N450D

This variant is defined by S:N450D and was first detected in USA. Now it is present in five other countries across two continents (105 seq on Usher as of 25.07.22).

Apparently there is a lot of convergent evolution taking place with regards to S:N450D as this mutation is concurrently arising in multiple "distant" BA.2 (#851, #772, #812, #814) and BA.5 (#843) lineages. ...

https://github.com/cov-lineages/pango-designation/issues/873
 
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