tetano
Editor, Senior Moderator
Virus Res. 2018 Jan 29;247:10-14. doi: 10.1016/j.virusres.2018.01.008. [Epub ahead of print]
[h=1]Β-defensins - Underestimated peptides in influenza combat.[/h] Kalenik BM[SUP]1[/SUP], G?ra-Sochacka A[SUP]1[/SUP], Sirko A[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Defensins are a family of host defense peptides present in vertebrates, invertebrates and plants. They display broad antimicrobial activity and immunomodulatory functions. Herein, the natural anti-influenzal role of β-defensins, as well as their potential usage as anti-influenza vaccine adjuvants and therapeutic agents, is reviewed. This article summarizes previously published information on β-defensin modes of action, expression changes after influenza infection and vaccination, biotechnological usage and possible boosting of their production by dietary supplementation.
[h=4]KEYWORDS:[/h] Antimicrobial peptides; Antivirals; Defensin; Dietary stimulation; Immunomodulation; Influenza
PMID: 29421304 DOI: 10.1016/j.virusres.2018.01.008
[h=1]Β-defensins - Underestimated peptides in influenza combat.[/h] Kalenik BM[SUP]1[/SUP], G?ra-Sochacka A[SUP]1[/SUP], Sirko A[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Defensins are a family of host defense peptides present in vertebrates, invertebrates and plants. They display broad antimicrobial activity and immunomodulatory functions. Herein, the natural anti-influenzal role of β-defensins, as well as their potential usage as anti-influenza vaccine adjuvants and therapeutic agents, is reviewed. This article summarizes previously published information on β-defensin modes of action, expression changes after influenza infection and vaccination, biotechnological usage and possible boosting of their production by dietary supplementation.
[h=4]KEYWORDS:[/h] Antimicrobial peptides; Antivirals; Defensin; Dietary stimulation; Immunomodulation; Influenza
PMID: 29421304 DOI: 10.1016/j.virusres.2018.01.008