tetano
Editor, Senior Moderator
Avian Pathol
. 2025 Mar 26:1-11.
doi: 10.1080/03079457.2025.2476511. Online ahead of print. The host protein CCT8 interacts with PB2 protein of H9N2 AIV and facilitates virus replication
Yiqin Cai[SUP] 1 2 [/SUP], Ye Liu[SUP] 1 2 [/SUP], Guihu Yin[SUP] 1 2 [/SUP], Jianing Hu[SUP] 1 2 [/SUP], Zichen Gao[SUP] 1 2 [/SUP], Xinyu Guo[SUP] 1 2 [/SUP], Ruiying Wang[SUP] 1 2 [/SUP], Meng Zhong[SUP] 1 2 [/SUP], Qingtao Liu[SUP] 1 3 [/SUP], Xiuli Feng[SUP] 1 2 [/SUP]
Affiliations
The host protein CCT8 interacts with the influenza virus protein PB2.The CCT8 gene is upregulated during influenza virus infection.Knockdown of CCT8 inhibits viral proliferation.Elevated expression of CCT8 facilitates viral proliferation.
Keywords: H9N2 avian influenza virus; PB2 protein; chaperonin containing TCP-1 subunit 8 (CCT8); host protein; mass spectrometry; viral replication.
. 2025 Mar 26:1-11.
doi: 10.1080/03079457.2025.2476511. Online ahead of print. The host protein CCT8 interacts with PB2 protein of H9N2 AIV and facilitates virus replication
Yiqin Cai[SUP] 1 2 [/SUP], Ye Liu[SUP] 1 2 [/SUP], Guihu Yin[SUP] 1 2 [/SUP], Jianing Hu[SUP] 1 2 [/SUP], Zichen Gao[SUP] 1 2 [/SUP], Xinyu Guo[SUP] 1 2 [/SUP], Ruiying Wang[SUP] 1 2 [/SUP], Meng Zhong[SUP] 1 2 [/SUP], Qingtao Liu[SUP] 1 3 [/SUP], Xiuli Feng[SUP] 1 2 [/SUP]
Affiliations
- PMID: 40135264
- DOI: 10.1080/03079457.2025.2476511
The host protein CCT8 interacts with the influenza virus protein PB2.The CCT8 gene is upregulated during influenza virus infection.Knockdown of CCT8 inhibits viral proliferation.Elevated expression of CCT8 facilitates viral proliferation.
Keywords: H9N2 avian influenza virus; PB2 protein; chaperonin containing TCP-1 subunit 8 (CCT8); host protein; mass spectrometry; viral replication.