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Avian Influenza Virus H11N2 Found In Antarctic Penguins

tetano

tetano

Editor, Senior Moderator
An international team of researchers has, for the first time, identified an avian influenza virus in a group of Ad?lie penguins from Antarctica. The virus, found to be unlike any other circulating avian flu, is described in a study published this week in mBio?, the online open-access journal of the American Society for Microbiology.

While other research groups have taken blood samples from penguins before and detected influenza antibodies, no one had detected actual live influenza virus in penguins or other birds in Antarctica previously, says study author and Associate Professor Aeron Hurt, PhD, a senior research scientist at the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne, Australia.


...


http://www.science20.com/news_artic...za_viruses_found_in_antarctic_penguins-135708
 
Re: Avian Influenza Virus H11N2 Found In Antarctic Penguins

http://www.eurekalert.org/pub_releases/2014-05/asfm-dai050114.php
found avian influenza virus (AIV) genetic material in eight (2.7%) Penguin samples
H11N2
unlike anything else
4 segments NA 1960s, 2 segments SA
molecular clock ... 49 to 80 years


waiting for the sequences ... how many amino-acid mutations in the inner segments,
how close to 1918flu
 
Re: Avian Influenza Virus H11N2 Found In Antarctic Penguins

http://mbio.asm.org/content/5/3/e01098-14

pdf, 10 pages, 845K: http://mbio.asm.org/content/5/3/e01098-14.full.pdf+html


Nucleotide sequence accession numbers. Full genome sequences
from the four H11N2 influenza viruses isolated in eggs have been depos-
ited in GenBank under accession numbers KJ729348 to KJ729379.

http://www.ncbi.nlm.nih.gov/nuccore/KJ729348

not yet available,



96 , North American avian 50 (41-58) years
89 , Equine H3N8 , 77 (61-100)
91 , Equine H3N8, South American avian 56 (50-69)
90 , North American avian ,50 (43-58)
96 , North American avian , 49 (41-58)
90 , North American avian/ new lineage 54 (50-60)
97 , North American avian, South American avian, 80 (56-112)
95 , North American avian , 56 (45-69)


recalling equine H3N8(1963) neighbours:
Code: 
   0    0 2280    2 >A/Equine/Miami/1/1963,1963//,H3N8,USA

-----------------1-----------------------
 685   82 1196 7248 >A/Ck/Chile/184240-5/2002,2002//,H7N3,Chile
 689   86 1247 1192 >A/Ck/Pakistan/1369-CR2/1995,1995//,H7N3,Pakistan
 694   87 1252 1199 >A/Ck/Pakistan/447/1995,1995//,H7N3,Pakistan
 741  169 2280 7012 >A/Tk/Canada/1963,1963//,H6N8,Canada
 742  169 2275 7013 >A/Tk/Canada/1963,1963//,H6N8,Canada
 745  170 2280 5950 >A/mallard/WI/169/1975,1975//,H5N3,USA
 750  171 2280 4090 >A/blue-winged teal/ALB/286/1977,1977/08/10,H3N6,Canada
 767  175 2280 4302 >A/canvasback Dk/ALB/274/1977,1977/08/09,H4N6,Canada
 767  175 2280 4673 >A/gadwall Dk/ALB/53/1977,1977/08/09,H4N6,Canada
 767  175 2280 7090 >A/Tk/Wisconsin/1/1966,1966//,H9N2,USA
-----------------2--------------------
 849   64  753 6857 >A/semi-palmated sandpiper/New Jersey/237/1990,1990/05/26,H3N6,USA
1011   34  336 3379 >A/Dk/IT/701/2005,2005//,H10N7,Italy
1039   34  327 1032 >A/Ck/Jordan/1540/2003,2003//,H9N2,Jordan
1071   36  336 7181 >A/mallard/New Zealand/223-31/2005,2005//,H4N6,New Zealand
1101   37  336 4585 >A/Dk/Ontario/05/00 ,2000//,H3N2,Canada
1348   84  623 5000 >A/mallard/Alberta/127/00,2000//,H3N8,Canada
1349  136 1008 5241 >A/mallard/CA/JN808/2006,2006/12/06,H4N2,USA
1354   63  465 4264 >A/Ck/Hidalgo/232/94 ,1994//,H5N2,Mexico
1396  130  931 7193 >A/mallard/New Zealand/527-11/2005,2005//,H4N6,New Zealand
1406   83  590 1162 >A/Ck/Nanchang/3-201/01,2001//,H3N6,China
1437  161 1120 4502 >A/cinnamon teal/CA/JN611/2006,2006/12/06,H7N3,USA
1439  153 1063 4675 >A/green-winged teal/CA/JN1323/2007,2007/01/20,H10N7,USA
1442  328 2274 4005 >A/blue-winged teal/ALB/286/1977,1977/08/10,H3N6,Canada
1444  145 1004 7280 >A/northern shoveler/CA/8855/2008,2008/11/05,Avian,H5N2,USA
1462  173 1183 7273 >A/mallard/CA/HKWF1971C/2008,2008/01/23,Avian,H7N7,USA
1463  204 1394 5970 >A/mallard/Wisconsin/2543/2009,2009/10/05,H3N2,USA
1464  168 1147 5335 >A/mallard/Interior Alaska/8BM3100/2008,2008/08/18,H8N4,USA
1468   94  640 7240 >A/kelp gull/Argentina/LDC4/2006,2006//,H13N9,Argentina
1468  196 1335 4674 >A/green-winged teal/CA/JN1114/2006,2006/12/30,H4N6,USA
1473  335 2274    1 >A/Human/Brevig Mission/1/1918,1918//,H1N1,USA
1473  335 2274 3995 >A/blue Gs/WI/711/1975,1975//,H5N2,USA
1481  337 2274 4532 >A/Dk/Memphis/546/1974,1974//,H11N9,USA
1482  183 1234 7187 >A/mallard/New Zealand/449-68/2004,2004//,H1N2,New Zealand
1484  167 1125 7183 >A/mallard/New Zealand/275-11/2005,2005//,H4N6,New Zealand
1485  105  707  539 >A/aquatic bird/Korea/JN-1/2005,2005//,H3N8,South Korea
1486  338 2274 4531 >A/Dk/Memphis/546/1974,1974//,H11N9,USA
1486  338 2274 7061 >A/Tk/Ontario/7732/1966,1966//,H5N9,Canada
1490  339 2274   14 >A/Human/Index/early human/1935,1935//,H1N1,USA
--------------------3--------------------
 729  157 2151    3 >A/equine/Gansu/7/2008(H3N8)
 967    6   62   25 >A/Ck/Egypt/F3/2006,2006/06/01,H5N1,Egypt
1036  223 2151 7224 >A/Ck/Chile/184240-1/2002,2002//,H7N3,Chile
1106  238 2151 7228 >A/cinnamon teal/Bolivia/4537/2001,2001//,H7N3,Bolivia
1115  240 2151 6834 >A/semipalmated sandpiper/Delaware/2144/2000,2000//,H11N6,USA
1125  242 2151 7234 >A/rosy-billed pochard/Argentina/CIP051-575/2007,2007/05/,H6N8,Argentina
1150   91  791 3439 >A/mallard/Italy/199/01,2001//,H7N3,Italy
1156   97  839  523 >A/aquatic bird/Korea/KN-4/2005,2005//,H3N8,South Korea
1157   86  743 5018 >A/mallard/Alberta/199/1999,1999//,H3N6,Canada
1178   87  738 5048 >A/mallard/Alberta/232/94,1994//,H6N8,Canada
1190  138 1159 5126 >A/mallard/Alberta/72/1994,1994/08/09,H3N6,Canada
1200   93  775 5128 >A/mallard/Alberta/76/94,1994//,H6N8,Canada
1205   92  763  872 >A/Ck/HK/NT142/03,2003//,H9N2,HK
1224  126 1029 5030 >A/mallard/Alberta/211/1998,1998//,H1N1,Canada
1231   59  479  484 >A/Pigeon/Nanchang/11-045/2000,2000//,H3N6,China
1234   80  648 6421 >A/pintail/Alberta/210/99,1999//,H4N6,Canada
1246   94  754 6392 >A/pintail/ALB/179/1993,1993//,H6N1,Canada
1251   96  767 6422 >A/pintail/Alberta/22/97,1997//,H2N9,Canada
1257  221 1758 7209 >A/sooty tern/Western Australia/7666/1984,1984//,mixed,Australia
----------------4--------------
 901  153 1698    2 >A/equine/Gansu/7/2008,2008//,H3N8,China
1661  103  620   80 >A/Teal/Norway/10_1575/2007,2007//,H3N8,Norway
1690  105  621   79 >A/Teal/Norway/10_1037/2010,2010//,H3N2,Norway
1693  105  620  255 >A/Dk/Italy/02/2008,2008/09/21,H3,Italy
1723  107  621  254 >A/Dk/Italy/01/2008,2008/09/21,H3,Italy
1724  104  603   64 >A/Mallard/Norway/10_627/2010,2010//,H3,Norway
1726  111  643 1013 >A/shoveler/Koymor/118/2009,2009/09/02,H3,Russia
1768  119  673 1016 >A/teal/Altai/69/2008,2008/10/17,H3N8,Russia
1813  136  750  496 >A/mallard/Alberta/49/1995,1995/08/05,mixed,H3,Canada
------------------5-------------------------
 540   10  185 5142 >A/mallard/CA/JN808/2006,2006/12/06,H4N2,USA
 567   85 1497 4107 >A/blue-winged teal/ALB/651/1978,1978/08/22,H6N2,Canada
 781   24  307 2475 >A/Dk/Vietnam/OIE-4439/2010,2010/10/,H6N6,Viet Nam
 794  119 1497 6950 >A/rosy-billed pochard/Argentina/CIP051-557/2007,2007/05/,H6N2,Argentina
 941  141 1497 6557 >A/semipalmated sandpiper/Delaware/2109/2000,2000//,H11N6,USA
1242  186 1497 3888 >A/American black Dk/Illinois/3854/2009,2009/11/15,H11N9,USA
1242  186 1497 4729 >A/laughing gull/Delaware/12/2006,2006/05/22,H9N2,USA
1242  186 1497 5702 >A/mallard/Quebec/11020/2006,2006/08/19,H3N2,Canada
------------------6---------------------------
 785  111 1413    2 >A/equine/Gansu/7/2008,2008//,H3N8,China
1613  228 1413  194 >A/Dk/New Jersey/2000,2000//,H3N8,USA
2043  140  685    3 >A/American black Dk/New Brunswick/19350/2006,2006/09/14,H3N8,Canada
2052  290 1413  643 >A/pintail Dk/Alberta/169/1980,1980/08/05,H3N8,Canada
2057  136  661  197 >A/Dk/Perak/2458/1989,1989//,H3N8,Malaysia
------------------7-----------------
 159    4  251 7502 >A/Tk/CA/6889/1980,1980//,H9N2,USA
 176    4  226 7456 >A/shorebird/Delaware/275/2001,2001//,H9N7,USA
 284    9  316 7432 >A/shorebird/Delaware/141/2002,2002//,H9N9,USA
 376   37  982 7504 >A/Tk/Canada/1963,1963//,H6N8,Canada
 386   38  982    3 >A/equine/Gansu/7/2008(H3N8)
 397   39  982 4351 >A/Canada Gs/Wisconsin/902/1975,1975//,H5N2,USA
 397   39  982 7569 >A/Tk/Ontario/6118/1968,1968//,H8N4,Canada
 407   40  981 7503 >A/Tk/Canada/1963,1963//,H6N8,Canada
 407   40  982 4550 >A/blue-winged teal/ALB/48/1978,1978/08/07,H6N5,Canada
 407   40  982 5360 >A/mallard Dk/ALB/761/1978,1978/08/25,H6N8,Canada
----------------------------------81-------------------
 178   15  838 5229 >A/African starling/England-Q/983/1979,1979//,H7N1,United Kingdom
 417   35  838    3 >A/equine/Gansu/7/2008,2008//,H3N8,China
 417   35  838 3965 >A/mallard Dk/ALB/676/1979,1979/08/13,H3N6,Canada
 441   37  838 4983 >A/Tk/Ontario/6213/1966,1966/06/11,mixed,Canada
 453   38  838  187 >A/Dk/Egypt/053/2005,2005/02/05,H6N2,Egypt
 453   38  838  248 >A/whiskered tern/Egypt/04/2004,2004/12/05,H6N2,Egypt
 453   38  838 4956 >A/Tk/Massachusetts/3740/1965,1965/06/11,H6N2,USA
 477   40  838 3824 >A/Dk/PA/486/1969,1969//,H6N1,USA
 477   40  838 4984 >A/Tk/Ontario/7732/1966,1966//,H5N9,Canada
 
Re: Avian Influenza Virus H11N2 Found In Antarctic Penguins

available now


4 penguin genomes :
amino-distance to the bird-index: 13,10,13,--,11,--,02,15 (=64)

[the distance table below was replaced with a better more complete version on 2014/05/20
the Wisconsin sequences from the 70s were only uploaded recently to genbank
and probably not known when the paper was written]

Code: 
   0    0 2280    1 >KJ729348,A/Adelie penguin/Antarctica/270/2013(H11N2)
----------segment 1------------- 
 385   88 2280 8014 >CY181248,A/mallard/Wisconsin/14/1974,1974//,USA,H4N6,Avian,1
 394   90 2280 7732 >CY178985,A/mallard/Wisconsin/82/1976,1976//,USA,H3N2,Avian,1
 399   91 2280 7731 >CY178977,A/mallard/Wisconsin/81/1976,1976//,USA,mixed,Avian,1
----------segment 2------------- 
 916   23  251 3289 >CY077582,A/mallard/New Zealand/1440-365/2005,2005//,New Zealand,H11N9,Avian,2
 982   33  336 9881 >GQ249059,A/duck/Ontario/05/00 ,2000//,Canada,H3N2,Avian,2
1009   76  753 12885 >CY101124,A/semi-palmated sandpiper/New Jersey/237/1990,1990/05/26,USA,H3N6,Avian,2
1116  254 2274 12947 >A/equine/Miami/1/1963(H3N8)
1275  290 2274 12948 >A/equine/Gansu/7/2008(H3N8)
1474  182 1234 12844 >CY077519,A/mallard/New Zealand/449-68/2004,2004//,New Zealand,H1N2,Avian,2
1516  219 1444 12898 >CY128530,A/American black duck/New Brunswick/03532/2009,2009/09/10,Canada,H4N6,Avian,2
1528  226 1479 12901 >CY136355,A/ruddy turnstone/Delaware Bay/2763/1987,1987/05/20,USA,H10N7,Avian,2
1534  349 2274    2 >xxxxxxxx,A/Brevig Mission/1/1918,1918/10/10,USA,H1N1,Human,0
1537  173 1125 12839 >CY077471,A/mallard/New Zealand/275-11/2005,2005//,New Zealand,H4N6,Avian,2
1547  352 2274 7703 >CY179801,A/mallard/Wisconsin/331/1975,1975//,USA,H6N2,Avian,2
1547  352 2274 9645 >FJ517336,A/blue goose/WI/711/1975,1975//,USA,H5N2,Avian,2
1552  353 2274 12421 >KF435047,A/duck/Manitoba/1953,1953//,Canada,H10N7,Avian,2
1553  174 1120 12832 >CY076822,A/cinnamon teal/California/JN611/2006,2006/12/06,USA,H7N3,Avian,2
----------segment 3------------- 
 860  185 2151 12886 >A/equine/Miami/1/1963,H3N8
 948  204 2151 10529 >GU053043,A/chicken/Chile/184240-1/2002,2002//,Chile,H7N3,Avian,3
 948  204 2151 1184 >CY015031,A/chicken/Chile/184240-4322/2002,2002//,Chile,H7N3,Avian,3
 957  206 2151  633 >AY303661,A/chicken/Chile/4957/02,2002//,Chile,H7N3,Avian,3
 957  206 2151 6571 >CY144215,A/semi-palmated sandpiper/Delaware/AI00-2327/2000,2000/05/24,USA,H11N2,Avian,3
 962  207 2151 10282 >GU051078,A/semipalmated sandpiper/Delaware/2144/2000,2000//,USA,H11N6,Avian,3
 962  207 2151 8658 >DQ525416,A/cinnamon teal/Bolivia/4537/2001,2001//,Bolivia,H7N3,Avian,3
 966  207 2142  634 >AY303662,A/chicken/Chile/4322/02,2002//,Chile,H7N3,Avian,3
 966  208 2151  632 >AY303660,A/chicken/Chile/176822/02,2002//,Chile,H7N3,Avian,3
 966  208 2151 6572 >CY144223,A/ruddy turnstone/Delaware/AI00-1460/2000,2000/05/21,USA,H11N2,Avian,3
1050  226 2151 3852 >CY096060,A/rosy-billed pochard/Argentina/CIP051-269/2007,2007/05/13,Argentina,H6N8,Avian,3
----------segment 4------------- 
2182  370 1695 4426 >A/ruddy turnstone/Delaware/2762/1987,1987/05/20,H11N2,USA
2536  429 1691 4790 >A/tern/Australia/752/1975,1975//,H11N9,Australia
2619  444 1695 4425 >A/ruddy turnstone/Delaware/2589/1987,1987/05/20,H11N1,USA
----------segment 5------------- 
 414   62 1497 9170 >EU743081,A/turkey/CO/118899/1972,1972//,USA,H5N2,Avian,5
 447   67 1497 12534 >M63777,A/gull/Maryland/5/1977,1977//,USA,H11N9,Avian,5
 460   69 1497 1184 >CY005809,A/gull/Maryland/19/1977,1977/04/04,USA,H2N9,Avian,5
----------segment 6------------- 
 950  134 1410 1196 >A/duck/Hong Kong/293/1978,1978//,H7N2
 950  134 1410 2400 >A/duck/Hong Kong/301/1978,1978//,H7N2
 950  134 1410 7488 >A/duck/Hokkaido/5/1977,1977//,H3N2
 971  137 1410 1951 >A/turkey/Wisconsin/1/1966,1966//,H9N2
----------segment 7------------- 
 121    1   82 11620 >HM355908,A/northern waterthrush/Maine/CTR-AIV21/2006,2006/08/05,USA,,Avian,7
 185    2  108 11608 >HM355896,A/western wood-pewee/Washington/CTR-AIV09/2006,2006/07/26,USA,,Avian,7
 239    6  251 8652 >DQ107491,A/turkey/California/6889/1980,1980//,USA,H9N2,Avian,7
 295   29  981 7845 >CY180212,A/mallard/Wisconsin/471/1976,1976//,USA,H3N8,Avian,7
 305   30  981 1020 >AY664420,A/blue-winged teal/Alberta/96/76 ,1976//,Canada,H4N8,Avian,7
 305   30  981 1288 >CY004756,A/mallard duck/ALB/210/1977,1977/08/30,Canada,H4N8,Avian,7
 305   30  981 7516 >CY177537,A/duck/Minnesota/23/1975,1975//,USA,mixed,Avian,7
 305   30  981 7876 >CY180461,A/duck/Minnesota/104/1974,1974//,USA,H4N6,Avian,7
 305   30  981 7877 >CY180469,A/duck/Minnesota/110/1974,1974//,USA,H4N6,Avian,7
 316   31  981 1285 >CY004736,A/redhead duck/ALB/74/1977,1977/08/08,Canada,H4N6,Avian,7
 316   31  981 7834 >CY180124,A/mallard/Wisconsin/73/1976,1976//,USA,H3N8,Avian,7
 316   31  981 7838 >CY180156,A/mallard/Wisconsin/283/1976,1976//,USA,H3N8,Avian,7
----------segment 8------------- 
 465   39  838 4480 >CY177606,A/blue-winged teal/Wisconsin/2/1974,1974//,USA,mixed,Avian,8
 477   40  838 4474 >CY177506,A/widgeon/Alabama/1278/1975,1975//,USA,H11N2,Avian,8
 477   40  838 4791 >CY181121,A/mallard/Wisconsin/18/1974,1974//,USA,H6N2,Avian,8
 513   43  838 4552 >CY178330,A/mallard/Wisconsin/261/1980,1980//,USA,H11N9,Avian,8


the paper (supplement table s1) shows as best matches:
Gene Closest match % identity
PB2 A/mallard/WI/169/1975 (H5N3) 96%
PB1 A/equine/Miami/1/1963 (H3N8) 89%
PA A/equine/Miami/1/1963 (H3N8) 91%
HA A/tern/Australia/752/1975 (H11N9) 90%
NP A/turkey/CO/118899/1972 (H5N2) 96%
NA A/turkey/Wisconsin/1/1966 (H9N2) 91%
MP A/blue-winged teal/Alberta/96/1976 (H4N8) 97%
NS A/blue-winged teal/ALB/778/1978 (H10N3) 95%






Code: 
AT-score , number of nucleotides from {A,T} 
divided by the number of all nucleotides
multiplied by 10000

in the 8 segments, = total (nucleotides) > name
5539,5567,5550,5864,5190,5588,5035,5441, = 5509(13126)   >KJ729348,A/Adelie penguin/Antarctica/270/2013(H11N2)
5561,5659,5620,5936,5310,5702,5152,5465, = 5586(13130)   >A/Brevig Mission/1/1918(H1N1)6
5526,5800,5578,6666,5377,6666,5285,5608, = 5561(10028)   >A/******/index/2009/02/01
5614,5690,5602,6666,5237,6666,5152,5501, = 5518(10028)   >A/swine/Germany/2/1981(H1N1)=1578 
5776,5879,5801,6666,5344,6666,5366,5584, = 5685(10028)   >A/Brisbane/59/2007/07/01(H1N1)
5526,5518,5620,6666,5257,6666,5132,5644, = 5476(10028)   >A/equine/Miami/1/1963(H3N8)
5543,5598,5606,6666,5156,6666,5061,6666, = 5458( 9193)   >1980//,A/Avian/Index/Africa,HxNx,South Africa,Avian
5543,5708,5620,6666,5237,6666,5224,6666, = 5519( 9193)   >2000,A/Avian/Index/Africa,HxNx,Egypt,Avian
5535,5650,5578,6666,5217,6666,5010,6666, = 5467( 9193)   >1980//,A/Avian/Index/Asia,HxNx,China,Avian
5535,5690,5560,6666,5237,6666,5101,6666, = 5485( 9193)   >A/Avian/Index/Asia
5578,5642,5555,6666,5197,6666,5071,6666, = 5473( 9193)   >1980//,A/Avian/Index/Europe,HxNx,Germany,Avian
5539,5584,5546,6666,5250,6666,5050,6666, = 5454( 9193)   >A/Avian/Index/Europe
5442,5721,5541,6666,5230,6666,5101,6666, = 5465( 9193)   >1980//,A/Avian/Index/North America,HxNx,USA,Avian
5464,5708,5606,6666,5223,6666,5101,6666, = 5481( 9193)   >A/Avian/Index/North America
5614,5738,5602,6666,5257,6666,5040,6666, = 5523( 9193)   >1980//,A/Avian/Index/Oceania/,HxNx,Australia
5644,5734,5629,6666,5377,6666,5050,6666, = 5557( 9193)   >A/Avian/Index/Ozeania
5421,5593,5550,6666,5203,6666,5040,6666, = 5419( 9193)   >A/Avian/Index/South America
5486,5620,5676,5802,5257,5751,5122,5441, = 5553(13133)   >Index 7 birds similar to BM18 plus BM18
5486,5659,5569,6666,5290,5592,5142,5608, = 5503(11391)   >A/Ck/Mexico/31381-7/1994,1994//(H5N2)
5565,5716,5676,6666,5337,5702,5234,5727, = 5586(11391)   >A/Ck/Guatemala/194573/2002,2002//(H5N2)
5530,5584,5546,6666,5223,5673,5183,5656, = 5501(11435)   >A/Ck/Guangdong/56/01,2001//,China,H9N2
5605,5580,5546,6666,5257,5695,5173,5632, = 5519(11426)   >A/Ck/Hebei/Y2/2009,2009/03/,China,H9N2
5434,5712,5527,6666,5203,6666,5061,5417, = 5445(10028)   >A/mallard/WI/42/1975,1975//,
5697,5778,5774,5778,5490,5951,5254,5704, = 5705(13136)   >A/duck/LA/17G/1987,1987//,H3N8
5692,5844,5885,5838,5524,5691,5295,5668, = 5718(13125)   >A/pekin duck/CA/P30/2006,2006/03/06,H4N2
5684,5847,5862,5808,5503,5874,5264,5632, = 5721(12926)   >A/cinnamon teal/CA/44287-325/2007,2007/01/27,H3N8
5526,5518,5620,5753,5257,5605,5132,5644, = 5525(13133)   >A/equine/Miami/1/1963,1963//,H3N8
5714,5778,5867,6048,5410,5909,5254,5918, = 5758(13133)   >A/equine/Gansu/7/2008,2008//,H3N8
6065,6156,6277,6187,5845,6163,5468,6161, = 6078(13157)   >A/equine/Lexington/1/1966(H7N7)
5666,5751,5741,5584,5357,5673,5203,5656, = 5613(13133)   >1972//,1643,RUS,A/Udorn/307/72
5719,5747,5746,5808,5437,5680,5244,5799, = 5673(13133)   >Index/2009/Egypt/Iowa
5561,5659,5620,5802,5310,5751,5152,5465, = 5574(13133)   >A/Brevig Mission/1/1918(H1N1)
5592,5760,5708,5778,5357,5716,5213,5453, = 5614(13133)   >A/Index/early human
5622,5760,5792,5812,5344,5663,5244,5477, = 5633(13085)   >A/Puerto Rico/8-1/1934(H1N1)
5776,5879,5801,5906,5344,5874,5366,5584, = 5733(13133)   >A/Brisbane/59/2007/07/01(H1N1)
5491,5765,5527,5767,5417,5695,5254,5548, = 5579(13133)   >A/Sw/Index/triple-reassortant/1998(H3N2)
5491,5773,5578,5737,5444,5716,5213,5584, = 5590(13133)   >A/Sw/Ontario/33853/2005(H3N2)
5526,5800,5578,5920,5377,5794,5285,5608, = 5632(13133)   >A/******/index/2009/02/01
5592,5703,5685,5837,5317,5829,5152,5465, = 5611(13133)   >A/Index/early Sw
5688,5853,5843,5967,5390,5851,5244,5501, = 5716(13133)   >A/New Jersey/11/1976(H1N1)
5697,5866,5857,5949,5417,5872,5315,5608, = 5738(13133)   >A/Sw/Iowa/24297/1991(H1N1)
5688,5901,5908,6019,5484,5851,5315,5632, = 5767(13133)   >A/Sw/Guangdong/34/2006(H1N1)
5614,5690,5602,5831,5237,5666,5152,5501, = 5574(13133)   >A/Sw/Germany/2/1981(H1N1)=1578 
5736,5708,5667,5878,5437,5872,5183,5746, = 5678(13139)   >A/Sw/Jiangsu/s15/2011,2011/02/05,
5460,5603,5560,5629,5281,5591,5030,5715, = 5500(13065)   >A/turkey/Italy/1067/99 ,1999/02/04,H7N1,1
5491,5621,5541,5677,5294,5628,5081,5787, = 5526(13065)   >A/turkey/Italy/1351/2001,2001/02/15,H7N1,1



segments 1,5,7,8 are closely related to Wisconsin mallards from the 70s
the common anchester could be this:

Code: 
>A/Index/Wisconsin/1970,segment 1
ATGGAGAGAATAAAAGAACTAAGAGATCTAATGTCACAGTCTCGCACCCGCGAGATACTCACAAAAACCACTGTGGACCATATGGCCATAATCAAAAAATACACATCAGGGAGACAAGAGAAGAACCCCGCACTCAGGATGAAGTGGATGATGGCGATGAAATATCCAATTACAGCAGATAAGAGGATAATGGAAATGATTCCCGAGAGGAATGAACAAGGGCAGACCCTCTGGAGCAAAACAAACGACGCCGGCTCAGACCGAGTAATGGTATCACCTCTGGCCGTGACATGGTGGAATAGGAATGGGCCAACAACAAGCACAGTTCACTATCCAAAAGTTTACAAAACTTATTTTGAAAAAGTTGAAAGATTAAAACATGGGACCTTTGGCCCCGTCCATTTTAGGAATCAAGTTAAGATAAGAAGGAGAGTTGACATAAACCCTGGCCATGCAGACCTCAGTGCTAAGGAGGCACAAGATGTCATCATGGAGGTTGTTTTCCCAAATGAAGTGGGAGCCAGAATACTAACGTCGGAATCACAACTGACAATAACCAAAGAGAAAAAAGAAGAACTCCAGGATTGTAAAATTGCCCCCTTGATGGTAGCATACATGCTAGAAAGAGAGTTGGTCCGCAAGACGAGATTCCTCCCGGTGGCTGGCGGAACAAGCAGTGTGTATATTGAAGTATTACATCTAACCCAGGGAACGTGCTGGGAGCAGATGTACACTCCAGGAGGGGAAGTGAGAAATGATGATGTTGACCAAAGCTTAATTATTGCTGCCAGGAATATAGTAAGAAGAGCAACAGTATCAGCAGACCCATTAGCATCTCTGTTGGAAATGTGCCACAGTACACAGATTGGTGGAATAAGGATGGTAGACATCCTTAGGCAGAATCCAACAGAGGAACAAGCCGTAGATATATGCAAGGCAGCAATGGGCTTGAGAATTAGCTCATCTTTCAGCTTTGGTGGATTCACTTTTAAAAGAACAAGTGGATCGTCAGTCAAGAGAGAAGAAGAAGTGCTTACGGGCAACCTTCAAACATTGAAAATAAGAGTGCATGAGGGGTATGAAGAGTTTACAATGGTCGGGAGGAGAGCAACAGCCATTCTCAGAAAGGCAACCAGGAGGTTGATTCAACTGATAGTAAGTGGGAGAGACGAACAGTCAATTGCTGAAGCAATAATTGTGGCCATGGTATTTTCGCAAGAGGATTGCATGATAAAGGCAGTCCGAGGTGATCTGAATTTTGTTAATAGAGCAAACCAGCGACTGAACCCCATGCATCAACTTTTGAGACATTTTCAAAAGGATGCAAAAGTGCTTTTCCAAAACTGGGGAATTGAACCCATCGACAATGTGATGGGAATGATTGGGATATTGCCCGACATGACTCCAAGTACAGAGATGTCACTGAGAGGAGTAAGAGTCAGCAAAATGGGAGTAGATGAGTACTCCAGCACAGAGAGGGTGGTGGTGAGCATTGACCGCTTTTTAAGAGTTCGAGACCAACGAGGAAATGTACTATTGTCCCCTGAAGAAGTCAGCGAAACACAAGGAACGGAAAAGCTAACAATAACTTATTCATCGTCAATGATGTGGGAGATCAATGGTCCTGAATCAGTGTTGGTCAATACTTACCAGTGGATCATCAGGAACTGGGAGACTGTGAAAATTCAATGGTCACAGGATCCCACAATGTTGTATAACAAGATGGAATTCGAGCCATTTCAGTCTCTGGTTCCTAAGGCAGCCAGAGGCCAATACAGCGGGTTCGTAAGGACCCTGTTCCAGCAGATGCGTGATGTGCTTGGAACATTTGACACTGTTCAGATAATAAAGCTTCTCCCTTTTGCTGCTGCTCCACCGGAACAGAGCAGGATGCAGTTCTCTTCCTTGACTGTGAATGTGAGAGGATCAGGAATGAGAATACTCGTGAGAGGTAATTCTCCAGTGTTCAACTACAACAAGGCCACCAAGAGGCTTACAGTCCTCGGAAAAGATGCAGGTGCACTGACTGAAGATCCAGATGAAGGCACAGCTGGAGTGGAGTCTGCTGTTCTGAGAGGGTTTCTCATCTTGGGCAAAGAAGACAAGAGATATGGTCCAGCATTAAGCATCAATGAACTGAGCAATCTTGCAAAAGGGGAGAAGGCTAATGTGCTAATTGGGCAAGGAGACGTAGTGTTGGTAATGAAACGGAAACGGGACTCTAGCATACTTACTGACAGCCAGACAGCGACCAAAAGAATTCGGATGGCCATCAATTAG
>A/Index/Wisconsin/1970,segment 5
ATGGCGTCTCAAGGCACCAAACGATCCTATGAGCAGATGGAAACCGGTGGGGAACGCCAGAATGCCACTGAAATCAGAGCATCTGTTGGGAGAATGGTTGGTGGAATTGGAAGGTTCTATGTACAGATGTGCACTGAACTCAAACTCAATGACTATGAAGGGAGACTTATCCAGAACAGTATAACAATAGAGAGAATGGTCCTCTCGGCATTTGATGAAAGGAGAAACAAATATCTGGAAGAGCATCCCAGTGCCGGAAAGGACCCTAAAAAGACTGGAGGTCCAATCTACAAGAGACGAGATGGAAAATGGATGCGAGAATTGATCCTGTATGATAAAGATGAAATCAGAAGGATTTGGCGTCAAGCGAATAATGGAGAAGACGCACCTGCTGGTCTTACCCATTTGATGATCTGGCATTCCAATCTGAATGACGCAACATACCAGAGAACAAGGGCTCTTGTGCGTACTGGTATGGATCCCAGGATGTGCTCTCTGATGCAAGGCTCAACTCTTCCGAGGAGATCAGGGGCAGCTGGAGCAGCAGTGAAAGGGGTCGGAACAATGGTGATGGAATTGATTCGGATGATTAAACGGGGAATCAATGATCGGAACTTCTGGAGAGGCGAAAATGGACGGAGAACAAGAATTGCATACGAAAGAATGTGCAACATTCTCAAAGGGAAATTCCAAACAGCAGCACAACGCGCAATGATGGACCAAGTGCGGGAAAGTCGAAATCCTGGGAATGCTGAGATCGAGGATCTTATCTTTCTTGCACGATCTGCTCTCATTCTGAGGGGATCAGTGGCTCATAAATCCTGCCTGCCTGCTTGTGTGTACGGACTTGCTGTGGCCAGCGGATACGACTTTGAGAGAGAGGGATACTCCCTTGTCGGGATTGACCCTTTCCGTCTGCTCCAGAACAGTCAAGTCTTCAGCCTTATCAGACCAAACGAAAATCCAGCACACAAAAGCCAGCTGGTATGGATGGCATGTCACTCTGCAGCATTTGAAGATCTGAGAGTATCTAGTTTCATCAGAGGGGCAAAAGTAGTTCCAAGAGGACAATTGTCCACCAGAGGGGTACAGATTGCTTCAAATGAGAACATGGAGACAATGGACTCCAGTACTCTTGAATTGAGAAGCAGATACTGGGCCATAAGGACCAGAAGTGGAGGGAACACTAACCAGCAGAGAGCATCTGCAGGACAAATCAGCGTACAGCCCACATTCTCTGTACAGAGAAATCTTCCATTCGAGAGAGCAACCATTATGGCGGCATTTACAGGAAACACTGAAGGCAGAACCTCGGATATGAGAACTGAGATCATAAGGATGATGGAAAATGCCAGGCCTGAAGATGTGTCTTTCCAGGGGCGGGGAGTCTTCGAGCTCTCGGACGAAAAGGCGACGAACCCGATCGTGCCTTCCTTTGACATGAGTAACGAGGGATCTTATTTCTTCGGAGACAATGCAGAGGAATATGACAATTGA
>A/Index/Wisconsin/1970,segment 7
ATGAGTCTTCTAACCGAGGTCGAAACGTACGTTCTCTCTATCGTCCCGTCAGGCCCCCTCAAAGCCGAGATCGCGCAGAGACTTGAAGATGTCTTTGCAGGGAAGAACACCGATCTTGAGGCACTCATGGAATGGCTAAAGACAAGACCAATCCTGTCACCTCTGACTAAGGGGATTTTAGGATTTGTGTTCACGCTCACCGTGCCCAGTGAGCGAGGACTGCAGCGTAGACGCTTTGTCCAGAATGCCCTTAATGGGAATGGAGATCCAAACAACATGGACAGGGCAGTCAAACTGTACAGGAAGCTCAAAAGGGAAATAACATTCCATGGGGCCAAAGAGGTAGCACTCAGTTATTCCACTGGTGCACTTGCCAGTTGCATGGGCCTCATATACAACAGAATGGGAACTGTGACCACCGAAGTGGCATTTGGCCTGGTGTGCGCCACATGTGAGCAGATTGCTGACTCCCAGCATCGGTCTCACAGACAGATGGTGACAACAACCAACCCACTGATCAGACATGAGAACAGAATGGTACTGGCCAGTACTACGGCTAAAGCCATGGAGCAGATGGCAGGGTCGAGTGAACAGGCAGCAGAGGCTATGGAGGTTGCTAGTCAGGCTAGGCAGATGGTGCAGGCAATGAGGACCATTGGGACTCATCCTAGCTCCAGTGCTGGTCTAAAAGATGATCTTCTTGAAAATTTGCAGGCCTACCAGAAACGGATGGGAGTGCAAATGCAGCGATTCAAGTGATCCTCTCGTTATTGCCGCAAGTATCATTGGGATCTTGCACTTGATATTGTGGATTCTTGATCGTCTTTTCTTCAAATGCATTTATCGTCGCCTTAAATACGGTTTGAAAAGAGGGCCTTCTACGGAAGGAGTGCCTGAGTCTATGAGGGAAGAATATCGGCAGGAACAGCAGAGTGCTGTGGATGTTGACGATGGTCATTTTGTCAACATAGAGCTGGAGTAA
>A/Index/Wisconsin/1970,segment 8
ATGGATTCCAACACTGTGTCAAGCTTTCAGGTAGACTGCTTTCTTTGGCATGTCCGCAAACGATTTGCAGACCAAGAACTGGGTGATGCCCCATTCCTTGACCGGCTTCGCCGAGATCAGAAATCCCTGAGAGGAAGAGGCAGCACTCTTGGTCTGGACATCGAAACAGCCACCCGTGCTGGAAAGCAGATAGTGGAGCGGATTCTAGAGGAAGAATCCGACGAGGCACTTAAAATGACTATTGCCTCTGTACCTGCTTCACGCTACCTAACTGACATGACTCTTGAGGAAATGTCAAGGGACTGGTTCATGCTCATGCCCAAGCAAAAAGTAGCAGGCTCCCTCTGTATCAGAATGGACCAGGCGATCATGGATAAGAATATCATACTGAAAGCGAATTTCAGTGTGATTTTCGACCGGCTGGAGACACTGATACTGCTCAGGGCTTTCACCGAAGAAGGGGCAATTGTCGGAGAAATTTCACCATTGCCTTCTCTTCCAGGACATACTGATGAGGATGTCAAAAATGCAATTGGGGTCCTCATCGGAGGACTTGAATGGAATGATAACACAGTTCGAGTCTCTGAAACTCTACAGAGATTCGCTTGGAGAAGCAGTAATGAGGATGGGAGACCTCCACTCCCTCCAAAGCAGAAACGGAAAATGGCGAGAACAATTGAGTCAGAAGTTTGAAGAAATAAGGTGGTTGATTGAAGAAGTGCGACATAGACTGAAGGTTACAGAGAATAGTTTTGAGCAGATAACATTTATGCAAGCCTTACAACTACTGCTTGAAGTGGAGCAAGAGATAAGAACTTTCTCGTTTCAGCTTATTTAA


--> 13 amino acid changes and 82 nucleotide changes in segment 1 in 43 years

to compare: mutations in segment 1 of
Qinghai H5N1 : 65 in 7 years,
human H3N2 : 170 in 44 years
equine H3N8 : 155 in 50 years
2013 H7N9 : 220 in 50 years
17g: 91 in 19 years
triple reassortant swine --> ****** . 65 in 11 years
Euroswine 1978 : 145 in 32 years
HK1975 ---> Mongolia 2007 : 54 in 32 years


it could have survived in cold Antarctica for some time outside penguins, without replicating/mutating
 
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