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Australian scientist using NZ samples to create vaccine

kiwibird

Editor, Senior Moderator
http://www.3news.co.nz/Australians-...bid/209/articleID/102034/cat/525/Default.aspx

Australians take NZ students' samples to create flu vaccine
Fri, 01 May 2009 5:39a.m.

A team of Australian scientists has appropriated samples of swine flu taken from the Rangitoto College group, to help develop a vaccine.

Scientists at the World Health Organisation (WHO) Influenza Centre in North Melbourne are injecting the virus taken from the New Zealanders into fertilised hens' eggs.

The samples were sent to the laboratory by New Zealand health officials, desperate to find out whether the group had contracted swine flu in Mexico.

Tests on the best four samples immediately showed three of them were infected, and it was this virus which was used by the Melbourne laboratory. The fourth sample was of poorer quality.

After cultivating the virus in the eggs, the Melbourne researchers will conduct a series of tests, then send it off to companies that manufacture vaccines, centre director Anne Kelso told The Age newspaper.

An effective vaccine would be worth millions of dollars if the influenza continues to cause serious illness internationally.

New Zealand already has a contract with the Australian government's Commonwealth Serum Laboratories (CSL) to be supplied with a pandemic vaccine within 15 to 27 weeks after a pandemic is recognised by the WHO.

Professor Kelso said the US is leading the international race for a vaccine, using viruses from Californian patients.

The number of suspected cases of swine flu in New Zealand was reported last night to have risen to 111, up from 96 on Wednesday.

The Ministry of Health said that the number of people in isolation was also up from 111 to 121.

But the number of people confirmed or being treated as confirmed swine flu cases remained at 13, all in the Auckland area.

The growth in suspect numbers was primarily due to including close family contacts from passengers on flights from affected countries, Health Minister Tony Ryall said yesterday.

In Mexico the deaths of 160 people have been blamed on swine flu, although Mexican health officials say the number of confirmed swine flu cases is only 99, including eight dead.

The WHO has declared a Phase 5 outbreak, the second-highest on its threat scale, indicating a pandemic could be imminent.

Thirty-three countries had now notified WHO they had either suspected or confirmed cases of swine flu.

Mr Ryall said New Zealand had now moved its status to "phase 5.1" but said that was not an escalation of pandemic planning.

The strategy remains to contain and mitigate the spread of the flu, he said.

Of the group of students from Auckland's Rangitoto College who returned from Mexico on Saturday, three had tested positive to swine flu.

There are 10 other people being treated as swine flu cases, having tested positive for influenza A -- of which swine flu is a subset.

More tests have been sent to the WHO accredited lab in Melbourne to be tested for swine flu and more influenza A results were expected shortly.

The Rangitoto College students' symptoms were reported to be no worse than normal winter flu.

Health authorities are now working on setting up a specialised influenza assessment centre at Middlemore Hospital, near Auckland's international airport.

Director-General of Health Stephen McKernan said a decision was likely over the next 24-hours on a preferred site for such a centre.

Deputy Director of Public Health Fran McGrath said scientists were monitoring any possible mutations of the flu.

The anti-viral drug Tamiflu will be available over the counter without a prescription from today to people showing signs of the flu.

Some chemists have criticised the move, saying it could be counterproductive as flu sufferers flocked to their local chemists and possibly spread it further.
 
Re: Australian scientist using NZ samples to create vaccine

An effective vaccine would be worth millions of dollars if the influenza continues to cause serious illness internationally.


this is about money not helping people surely a vaccine made this early would not be effective.the virus would have changed by the time it was ready.
 
Re: Australian scientist using NZ samples to create vaccine

Yes - you would think so. I should have thought that the very fact that the strain we have at present is tamiflu sensitive would make it not worth while developing a vaccine. It is the vaccine for the resistant one I would want to have!
 
Re: Australian scientist using NZ samples to create vaccine

Tamiflu resistance (or not) may not make a difference to the antigens that they wanted the vaccine recipient to recognise and have immunological memory of though.
 
Re: Australian scientist using NZ samples to create vaccine

I'll take the first one off the production line - I don't care where it come from.

this may take 2 shots 28 days apart, so the quicker, the better.

a contract with the Australian government's Commonwealth Serum Laboratories (CSL) to be supplied with a pandemic vaccine within 15 to 27 weeks after a pandemic is recognised by the WHO.

That's a tight schedule for getting a version that will grow successfully; testing for strength, safety, etc.; approvals; and production.

.
 
Re: Australian scientist using NZ samples to create vaccine

Australian scientists working on swine flu vaccine

Sat, 02 May 2009 4:02p.m.

A team of Australian scientists have begun work on samples of swine flu taken from the Rangitoto College group, to help develop a vaccine.

Scientists at the World Health Organisation Centre in Melbourne are injecting the virus into fertilised hens' eggs, and it is hoped the first doses of the new vaccine will be available to the public in 12 weeks.

Scientists say the virus will grow on the membrane in very high concentration, and in a couple of weeks those samples will be sent to drug companies for the development of a swine flu vaccine.

"Normally the seasonal influenza vaccine takes six months to prepare, so if you're planning to make a brand new flu vaccine with a new virus it could take some months," says Prof Anne Kelso.

Scientists say it will be three months before the first dose of swine flu vaccine will be available, but what is important is that it will be ready in time for our flu season - at its peak in August and September.

In the meantime New Zealand health authorities are focussed on stopping the spread. The number of confirmed cases here remains at four, there are 12 more that are probable.

From today every single passenger arriving from overseas flights has to fill in a passenger locator form.

Passengers leaving Auckland to fly to Niue will be screened for flu symptoms at the request of the Niuean government.

"There's only one flight in and out of Niue each way, and having had an influenza outbreak there not too long ago the Niuean government is keen to do everything it can to manage this," says Health Minister Tony Ryall.

It was only a matter of time before swine flu made its way in to Asia.
Hong Kong authorities confirmed their first case came from a Mexican man who had recently flown in from China. The hotel where the man was staying was immediately sealed off, and 300 guests and staff were not allowed to leave.

Worldwide 15 countries have confirmed cases, but almost all infections outside Mexico have been mild.

http://www.3news.co.nz/News/Nationa...abid/423/articleID/102255/cat/65/Default.aspx
 
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