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AU: Emergence of a ribotype 244 strain of Clostridium difficile associated with severe disease and related to the epidemic ribotype 027 strain

Shiloh

Editor, Senior Moderator
Source: http://cid.oxfordjournals.org/content/early/2014/04/03/cid.ciu203.abstract

Emergence of a ribotype 244 strain of Clostridium difficile associated with severe disease and related to the epidemic ribotype 027 strain

Correspondence: Grant A. Jenkin Monash Infectious Diseases, Monash Health, Clayton Rd, Clayton 3168, Victoria, Australia Ph 61 3 9594 4564; Fax 61 3 9594 4533. Grant.Jenkin@monash.edu

Abstract

Background. We identified 12 patients with Clostridium difficile infection between July 2011 and March 2012 from whom an unusual C. difficile strain was isolated. This strain had a single nucleotide deletion of the tcdC gene at position 117 and binary toxin genes which are characteristic of the hypervirulent ribotype 027 (RT027) strain...
 
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