• FluTrackers.com Inc. does not provide medical advice. Information on this web site is collected from various internet resources, and the FluTrackers board of directors makes no warranty to the safety, efficacy, correctness or completeness of the information posted on this site by any author or poster. The information collated here is for instructional and/or discussion purposes only and is NOT intended to diagnose or treat any disease, illness, or other medical condition. Every individual reader or poster should seek advice from their personal physician/healthcare practitioner before considering or using any interventions that are discussed on this website. By continuing to access this website you agree to consult your personal physican before using any interventions posted on this website, and you agree to hold harmless FluTrackers.com Inc., the board of directors, the members, and all authors and posters for any effects from use of any medication, supplement, vitamin or other substance, device, intervention, etc. mentioned in posts on this website, or other internet venues referenced in posts on this website.
  • We are not asking for any donations. Do not donate to any entity who says they are raising funds for us.

AstraZeneca to buy MedImmune

Niko

Editor, Senior Moderator
AstraZeneca to buy MedImmune for $15.6B Deal gives British drug maker entry into vaccines market

sourceAP.gif
Updated: 7:40 a.m. ET April 23, 2007<script language="javascript"> function UpdateTimeStamp(pdt) { var n = document.getElementById("udtD"); if(pdt != '' && n && window.DateTime) { var dt = new DateTime(); pdt = dt.T2D(pdt); if(dt.GetTZ(pdt)) {n.innerHTML = dt.D2S(pdt,((''.toLowerCase()=='false')?false:true));} } } UpdateTimeStamp('633129252477600000');</script>

LONDON - AstraZeneca PLC said Monday it is buying U.S.-based biotech drugmaker MedImmune Inc. in a US$15.6 billion deal that will allow the British company to enter the vaccines market.

AstraZeneca, which has been looking to strengthen its pipeline of future drugs as it faces patent challenges and escalating generic competition, will pay $58 a share for MedImmune, a 21 percent premium to the stock's close on Friday.

"This acquisition represents a transformational step to deliver our biologics strategy sooner than anticipated," said AstraZeneca Chief Executive David Brennan. "It creates a leading fully integrated biologics and vaccines business with critical mass and enhances AstraZeneca's R&D science base through which we will deliver a stronger product pipeline."

The deal, which AstraZeneca hopes to close in June, will increase the company's proportion of biotechnology drugs in its pipeline from 7 percent to 27 percent, and enlarge its total pipeline by 45 projects to 163 projects.
That includes two late-stage products being developed by Gaithersburg, Maryland-based MedImmune, which has more than 2,500 employees in facilities across the United States, Britain and the Netherlands.

One product is a next-generation follow-on to its flagship childhood respiratory drug Synagis. The second is a refrigerated formulation of its FluMist inhaled influenza vaccine, which will probably be launched in the coming U.S. winter season.

AstraZeneca's decision to enter the vaccines market follows the purchase of U.S. vaccines maker Chiron by Novartis AG last year. AstraZeneca's British rival, GlaxoSmithKline PLC, and Paris-based Sanofi-Aventis SA already have large vaccines business.

Pharmaceutical companies are turning to vaccines as a new growth area because the market has few producers and a reduced risk of generic competition. Interest was spurred on by the emergence of the deadly strain of bird flu in Asia and the resulting realization that there was no vaccine to protect against it.

Brennan said that the bidding process for MedImmune was "ferociously competitive" and that Astra was "delighted to have won against all of our peers in the pharma industry."

MedImmune said earlier this month that it was willing to consider takeover offers, reversing its stand against a sale because of interest from big pharmaceutical companies and investor unhappiness with the company's performance.

The company posted US$1.28 billion (??940 million) in revenue last year, mostly from Synagis, but investors said it had failed to meet some major milestones.

Shareholder concerns centered on the disappointing launch of FluMist four years ago. The drug was predicted to be a blockbuster, but ran into problems with storage, price and limitations on who could use it.

The announcement of the deal with MedImmune led Astra to bring forward its release of its first-quarter results, originally scheduled for Wednesday.

The company reported a 9.5 percent increase in net profit of $1.56 billion. Revenue rose 13 percent to $6.97 billion as the company benefited from the strong dollar while sales at constant exchange rates rose at a slower pace of 9 percent.

Astra said it was still on track for reaching its target earnings per share in 2007 of $3.80 to $4.05, excluding any contribution from U.S. sales of heart drug Toprol-XLTM and restructuring costs.

It said it expects to incur a $250 million charge relating to supply chain restructuring in 2007, about half the total it expects for the restructuring.
AstraZeneca shares fell 1.5 percent to 2,910 pence on the London Stock Exchange.

Copyright 2007 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
 
Re: AstraZeneca to buy MedImmune

are they going to produce panflu vaccine now ?


they are in phase 1 - testing with their H5N1-vaccine according to :

http://www.medimmune.com/pipeline/index.asp

so, I assume it will take another 1-2 years. Other vaccines seem
to have larger priority, though maybe Astra Seneca may change this now...


last story about medimmunes H5N1-vaccine
http://sev.prnewswire.com/medical-pharmaceuticals/20070329/DCTH05829032007-1.html
says, that they licensed their reverse genetics method to Sanofi.

Almost at the same time when FDA approved the Sanofi prepandemic vaccine,
although it was not very efficient,required higher doses and was more expensive
than Glaxo,Baxter vaccines.
So it seems that Astra-Seneca and Sanofi-Pasteur are cooperating now
on prepandemic H5N1 vaccine. But medimmune continues to test its
own H5N1 intranasal vaccine.
 
Last edited:
Back
Top