tetano
Editor, Senior Moderator
J Anim Sci Biotechnol. 2013 Jun 21;4(1):22. [Epub ahead of print]
Astragalus polysaccharide enhances immunity and inhibits H9N2 avian influenza virus in vitro and in vivo.
Kallon S, Li X, Ji J, Xi Q, Ma J, Xie Q, Zhang Y.
Abstract
This study investigated the humoral immunization of Astragalus polysaccharide (APS) against the infection of H9N2 avian influenza virus (H9N2 AIV) in chickens.The effects of APS treatment on H9N2 infection were investigated by MTT [3(4, 5-dimethylthiazol-2-yl)-2, 3-diphenyl tetrazolium bromide] assay and analysis of MHC and cytokines mRNA expression. The in vivo effects on lymphocytes and serum antibody titers were also investigated. The IL-4, IL-6, IL-10, LITAF, IL-12 and antibody titers to H9N2 AIV were enhanced in the first week after APS treatment. The results indicated that APS treatment reduces H9N2 AIV replication and promote early humoral immune responses in young chickens.
PMID:
23786718
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23786718
Astragalus polysaccharide enhances immunity and inhibits H9N2 avian influenza virus in vitro and in vivo.
Kallon S, Li X, Ji J, Xi Q, Ma J, Xie Q, Zhang Y.
Abstract
This study investigated the humoral immunization of Astragalus polysaccharide (APS) against the infection of H9N2 avian influenza virus (H9N2 AIV) in chickens.The effects of APS treatment on H9N2 infection were investigated by MTT [3(4, 5-dimethylthiazol-2-yl)-2, 3-diphenyl tetrazolium bromide] assay and analysis of MHC and cytokines mRNA expression. The in vivo effects on lymphocytes and serum antibody titers were also investigated. The IL-4, IL-6, IL-10, LITAF, IL-12 and antibody titers to H9N2 AIV were enhanced in the first week after APS treatment. The results indicated that APS treatment reduces H9N2 AIV replication and promote early humoral immune responses in young chickens.
PMID:
23786718
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23786718