tetano
Editor, Senior Moderator
J Infect Dis. 2015 Feb 2. pii: jiv058. [Epub ahead of print]
[h=1]Association of oseltamivir treatment with virus shedding, illness, and household transmission of influenza viruses.[/h] Cheung DH[SUP]1[/SUP], Tsang TK[SUP]2[/SUP], Fang VJ[SUP]2[/SUP], Xu J[SUP]2[/SUP], Chan KH[SUP]3[/SUP], Ip DK[SUP]2[/SUP], Peiris JS[SUP]4[/SUP], Leung GM[SUP]2[/SUP], Cowling BJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In an observational study of 582 patients with laboratory-confirmed influenza virus infections, and their household contacts, we found that the initiation of oseltamivir within 24h was associated with shorter duration of self-reported illness symptoms (56% reduction in duration; 95% CI: 41%-67%). However we did not find any association of oseltamivir treatment with duration of viral shedding by PCR, or with the risk of household transmission.
? The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
PMID: 25646354 [PubMed - as supplied by publisher]
[h=1]Association of oseltamivir treatment with virus shedding, illness, and household transmission of influenza viruses.[/h] Cheung DH[SUP]1[/SUP], Tsang TK[SUP]2[/SUP], Fang VJ[SUP]2[/SUP], Xu J[SUP]2[/SUP], Chan KH[SUP]3[/SUP], Ip DK[SUP]2[/SUP], Peiris JS[SUP]4[/SUP], Leung GM[SUP]2[/SUP], Cowling BJ[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In an observational study of 582 patients with laboratory-confirmed influenza virus infections, and their household contacts, we found that the initiation of oseltamivir within 24h was associated with shorter duration of self-reported illness symptoms (56% reduction in duration; 95% CI: 41%-67%). However we did not find any association of oseltamivir treatment with duration of viral shedding by PCR, or with the risk of household transmission.
? The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
PMID: 25646354 [PubMed - as supplied by publisher]