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Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers - JAMA

Mary Wilson

Well-known member
July 1, 2022

doi:10.1001/jama.2022.11691

Elena Azzolini, MD, PhD[SUP]1[/SUP]; Riccardo Levi, MSc[SUP]2[/SUP]; Riccardo Sarti, MSc[SUP]2[/SUP]; et al

Survivors of COVID-19 may present with long-lasting symptoms.[SUP]1[/SUP] Some factors have been associated with the development of post-COVID conditions (also referred to as “long COVID”),[SUP]2[/SUP] including hospitalization.[SUP]3[/SUP] A study of older US veterans showed 15% reduction of long COVID after vaccination; however, study limitations included the low number of women and suboptimal vaccination schedules.[SUP]4[/SUP]

Methods

The study was approved by the Humanitas Research Hospital institutional review board. Each participant provided written informed consent.

We conducted an observational cohort study from March 2020 to April 2022 in individuals working in 9 Italian health care facilities.[SUP]5[/SUP][SUP],6[/SUP] Polymerase chain reaction (PCR) tests for SARS-CoV-2 were conducted every week (in COVID wards) or 2 weeks (in other wards) for hospital personnel, or if they developed symptoms or were exposed to cases. All health care workers were required to receive 3 doses of vaccine (BNT162b2), with the first and second doses administered in January-February 2021 and the booster dose in November-December 2021. ...

https://jamanetwork.com/journals/ja...le_alert-jama&utm_content=olf&utm_term=070122
 
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