tetano
Editor, Senior Moderator
Infect Chemother. 2014 Sep;46(3):209-15. doi: 10.3947/ic.2014.46.3.209. Epub 2014 Sep 24.
Aspergillus Tracheobronchitis and Influenza A Co-infection in a Patient with AIDS and Neutropenia.
Lee JY1, Joo EJ1, Yeom JS1, Song JU1, Yim SH1, Shin DS1, Yu JH1, Ju DY1, Yim JW1, Song YS1, Sohn YJ1, Do SI2.
Author information
Abstract
Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) are known to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is only one reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patient with influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. We present a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid use or immunosuppressive therapy.
KEYWORDS:
AIDS; Aspergillus; Bronchitis; Influenza
PMID:
25298912
[PubMed]
http://www.ncbi.nlm.nih.gov/pubmed/25298912
Aspergillus Tracheobronchitis and Influenza A Co-infection in a Patient with AIDS and Neutropenia.
Lee JY1, Joo EJ1, Yeom JS1, Song JU1, Yim SH1, Shin DS1, Yu JH1, Ju DY1, Yim JW1, Song YS1, Sohn YJ1, Do SI2.
Author information
Abstract
Aspergillus tracheobronchitis (AT), an unusual form of invasive pulmonary aspergillosis (IPA), is characterized by pseudomembrane formation, ulcer or obstruction that is predominantly confined to tracheobronchial tree. Hematologic malignancies, neutropenia, solid organ transplantation, chronic corticosteroid therapy and acquired immunodeficiency syndrome (AIDS) are known to be major predisposing conditions. However, since the introduction of highly active antiretroviral therapy, there is only one reported case of AT in AIDS patient. After pandemic of influenza A/H1N1 2009, there are several reports of IPA in patient with influenza and most of them received corticosteroid or immunosuppressive therapy before the development of IPA. We present a 45 year-old AIDS patient with influenza A infection who developed pseudomembranous AT without corticosteroid use or immunosuppressive therapy.
KEYWORDS:
AIDS; Aspergillus; Bronchitis; Influenza
PMID:
25298912
[PubMed]
http://www.ncbi.nlm.nih.gov/pubmed/25298912