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Arthritis Rheumatol. On the alert for cytokine storm: Immunopathology in COVID-19

tetano

Editor, Senior Moderator
Arthritis Rheumatol. 2020 Apr 15. doi: 10.1002/art.41285. [Epub ahead of print]
On the alert for cytokine storm: Immunopathology in COVID-19.


Henderson LA[SUP]1[/SUP], Canna SW[SUP]2[/SUP], Schulert GS[SUP]3[/SUP], Volpi S[SUP]4[/SUP], Lee PY[SUP]1[/SUP], Kernan KF[SUP]5[/SUP], Caricchio R[SUP]6[/SUP], Mahmud S[SUP]7[/SUP], Hazen MM[SUP]1[/SUP], Halyabar O[SUP]1[/SUP], Hoyt KJ[SUP]1[/SUP], Han J[SUP]8[/SUP], Grom AA[SUP]3[/SUP], Gattorno M[SUP]4[/SUP], Ravelli A[SUP]9[/SUP], de Benedetti F[SUP]10[/SUP], Behrens EM[SUP]11[/SUP], Cron RQ[SUP]12[/SUP], Nigrovic PA[SUP]1,[/SUP][SUP]13[/SUP].

Author information




Abstract

Coronavirus disease 2019 (COVID-19) is sweeping across the globe. Most patients have mild to moderate symptoms, but a subgroup will become severely ill. Sepsis, respiratory failure, and acute respiratory distress syndrome (ARDS) are common complications of the disease.(1) Factors associated with ICU admission and death include older age, comorbid conditions, elevated body mass index, lymphopenia, and elevated transaminases, LDH, D-dimer, ferritin, and soluble IL-2 receptor (sIL-2R).(1-4).
This article is protected by copyright. All rights reserved.



PMID:32293098DOI:10.1002/art.41285
 
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