tetano
Editor, Senior Moderator
Arthritis Rheumatol
. 2020 May 26.
doi: 10.1002/art.41380. Online ahead of print.
Mild Course of Coronavirus Disease 2019 and Spontaneous Severe Acute Respiratory Syndrome Coronavirus 2 Clearance in a Patient With Depleted Peripheral Blood B-cells Due to Treatment With Rituximab
Benedict Fallet[SUP] 1 [/SUP], Diego Kyburz[SUP] 1 [/SUP], Ulrich A Walker[SUP] 1 [/SUP]
Affiliations
Abstract
Over 4 million cases of Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been confirmed worldwide. Up to 20% of cases develop severe disease and the fatality rate are high.[1] Little is known however on the course of the infection in immunosuppressed patients. We therefore report the case of a patient with COVID-19 under immunosuppression with rituximab. This 77-year-old woman was admitted to the hospital with a 5-week history of unclear fever (up to 38.5?C), hypotension (80 mmHg systolic on self-measurement), occasional mild shortness of breath and intermittent dry cough.
. 2020 May 26.
doi: 10.1002/art.41380. Online ahead of print.
Mild Course of Coronavirus Disease 2019 and Spontaneous Severe Acute Respiratory Syndrome Coronavirus 2 Clearance in a Patient With Depleted Peripheral Blood B-cells Due to Treatment With Rituximab
Benedict Fallet[SUP] 1 [/SUP], Diego Kyburz[SUP] 1 [/SUP], Ulrich A Walker[SUP] 1 [/SUP]
Affiliations
- PMID: 32458534
- DOI: 10.1002/art.41380
Abstract
Over 4 million cases of Coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been confirmed worldwide. Up to 20% of cases develop severe disease and the fatality rate are high.[1] Little is known however on the course of the infection in immunosuppressed patients. We therefore report the case of a patient with COVID-19 under immunosuppression with rituximab. This 77-year-old woman was admitted to the hospital with a 5-week history of unclear fever (up to 38.5?C), hypotension (80 mmHg systolic on self-measurement), occasional mild shortness of breath and intermittent dry cough.