tetano
Editor, Senior Moderator
Arch Virol
. 2026 Nov 8;171(12):317.
doi: 10.1007/s00705-026-06754-7.
Muhammad Awais Ashraf # 1 2 , Lihuan Yue # 1 , Muhammad Asif Raza 1 2 , Bei Shen 1 , Huiting Xu 3 , Muhammad Nabeel Amjad 1 2 , Ghayyas Ud Din 1 2 , Lingdie Chen 1 2 , Rongrong Hu 4 , Yuan Tian 4 , Ahsan Ali Bhutto 1 2 , Aguang Dai 5 , Huajie Yan 6 , Yihong Hu 7 8
Affiliations Expand
Influenza B virus, a member of the Orthomyxoviridae family, is a significant contributor to global respiratory infections alongside influenza A virus. This study investigated the prevalence and genomic characteristics of influenza B virus during the 2023-2024 season in Shanghai, China. Among 174 clinical samples collected from the Nanxiang Branch of Ruijin Hospital, the positivity rate for influenza B virus was 62.36%. Genomic analysis revealed that all characterized isolates belonged to the B/Victoria lineage and were classified within subclade C.5.7, corresponding to the legacy designation V1A.3a.2. No B/Yamagata lineage strains were detected. Comparative genomic analysis further revealed close genetic similarity between the Shanghai isolates and strains from Shanxi Province, suggesting a potential geographical or evolutionary relationship. These findings highlight the substantial activity of influenza B virus in Shanghai during the study period and underscore the importance of continued genomic surveillance to monitor viral evolution and inform public health strategies.
. 2026 Nov 8;171(12):317.
doi: 10.1007/s00705-026-06754-7.
Isolation, identification and whole genome sequence analysis of influenza B virus from Shanghai during 2023-2024
Muhammad Awais Ashraf # 1 2 , Lihuan Yue # 1 , Muhammad Asif Raza 1 2 , Bei Shen 1 , Huiting Xu 3 , Muhammad Nabeel Amjad 1 2 , Ghayyas Ud Din 1 2 , Lingdie Chen 1 2 , Rongrong Hu 4 , Yuan Tian 4 , Ahsan Ali Bhutto 1 2 , Aguang Dai 5 , Huajie Yan 6 , Yihong Hu 7 8
Affiliations Expand
- PMID: 43000490
- PMCID: PMC13745405
- DOI: 10.1007/s00705-026-06754-7
Abstract
Influenza B virus, a member of the Orthomyxoviridae family, is a significant contributor to global respiratory infections alongside influenza A virus. This study investigated the prevalence and genomic characteristics of influenza B virus during the 2023-2024 season in Shanghai, China. Among 174 clinical samples collected from the Nanxiang Branch of Ruijin Hospital, the positivity rate for influenza B virus was 62.36%. Genomic analysis revealed that all characterized isolates belonged to the B/Victoria lineage and were classified within subclade C.5.7, corresponding to the legacy designation V1A.3a.2. No B/Yamagata lineage strains were detected. Comparative genomic analysis further revealed close genetic similarity between the Shanghai isolates and strains from Shanxi Province, suggesting a potential geographical or evolutionary relationship. These findings highlight the substantial activity of influenza B virus in Shanghai during the study period and underscore the importance of continued genomic surveillance to monitor viral evolution and inform public health strategies.