tetano
Editor, Senior Moderator
Arch Med Sci
. 2021 Mar 18;17(3):818-822.
doi: 10.5114/aoms/134211. eCollection 2021.
COVID-19 and cardiovascular complications - preliminary results of the LATE-COVID study
Joanna Lewek[SUP] 1 2 [/SUP], Izabela Jatczak-Pawlik[SUP] 1 3 [/SUP], Marek Maciejewski[SUP] 2 [/SUP], Piotr Jankowski[SUP] 3 [/SUP], Maciej Banach[SUP] 1 3 4 [/SUP]
Affiliations
Abstract
Introduction: Coronavirus disease 2019 (COVID-19) may affect many organs and may be responsible for numerous complications including cardiovascular problems.
Methods: We analysed consecutive patients (n = 51) admitted to the cardiology department between 1[SUP]st[/SUP] October 2020 and 31[SUP]st[/SUP] January 2021 due to symptoms which might have reflected cardiovascular complications following COVID-19. We collected data concerning clinical characteristics, results of laboratory tests, echocardiography and 24-hour ambulatory ECG recording.
Results: The post-COVID-19 complications appeared 1-4 months after disease recovery. Severe cardiovascular complications were observed in 27.5% of hospitalized patients. In comparison to those with mild complications, patients with severe complications had significantly higher prevalence of diabetes (36 vs. 8%; p = 0.01), decrease in ejection fraction (36% vs. 0%, p < 0.001), higher resting heart rate at admission (85 vs. 72 bpm; p < 0.001), and higher levels of C-reactive protein (p = 0.02) and troponin T (17.9 vs. 4.2 pg/ml; p = 0.01). Dyspnoea and exercise intolerance were also more frequent in patients with severe complications.
Conclusions: Diabetes, elevated level of CRP and troponin, heart rate variability parameters and worsening of left ventricular ejection fraction are related to the severity of cardiovascular complications following COVID-19 infection.
Keywords: COVID-19; autonomic dysregulation; cardiovascular complications; decrease in left ventricular ejection fraction; myocarditis.
. 2021 Mar 18;17(3):818-822.
doi: 10.5114/aoms/134211. eCollection 2021.
COVID-19 and cardiovascular complications - preliminary results of the LATE-COVID study
Joanna Lewek[SUP] 1 2 [/SUP], Izabela Jatczak-Pawlik[SUP] 1 3 [/SUP], Marek Maciejewski[SUP] 2 [/SUP], Piotr Jankowski[SUP] 3 [/SUP], Maciej Banach[SUP] 1 3 4 [/SUP]
Affiliations
- PMID: 34025853
- PMCID: PMC8130484
- DOI: 10.5114/aoms/134211
Abstract
Introduction: Coronavirus disease 2019 (COVID-19) may affect many organs and may be responsible for numerous complications including cardiovascular problems.
Methods: We analysed consecutive patients (n = 51) admitted to the cardiology department between 1[SUP]st[/SUP] October 2020 and 31[SUP]st[/SUP] January 2021 due to symptoms which might have reflected cardiovascular complications following COVID-19. We collected data concerning clinical characteristics, results of laboratory tests, echocardiography and 24-hour ambulatory ECG recording.
Results: The post-COVID-19 complications appeared 1-4 months after disease recovery. Severe cardiovascular complications were observed in 27.5% of hospitalized patients. In comparison to those with mild complications, patients with severe complications had significantly higher prevalence of diabetes (36 vs. 8%; p = 0.01), decrease in ejection fraction (36% vs. 0%, p < 0.001), higher resting heart rate at admission (85 vs. 72 bpm; p < 0.001), and higher levels of C-reactive protein (p = 0.02) and troponin T (17.9 vs. 4.2 pg/ml; p = 0.01). Dyspnoea and exercise intolerance were also more frequent in patients with severe complications.
Conclusions: Diabetes, elevated level of CRP and troponin, heart rate variability parameters and worsening of left ventricular ejection fraction are related to the severity of cardiovascular complications following COVID-19 infection.
Keywords: COVID-19; autonomic dysregulation; cardiovascular complications; decrease in left ventricular ejection fraction; myocarditis.