tetano
Editor, Senior Moderator
Arch Med Res. 2020 Apr 4. pii: S0188-4409(20)30378-7. doi: 10.1016/j.arcmed.2020.03.011. [Epub ahead of print]
Is the ACE2 Overexpression a Risk Factor for COVID-19 Infection?
Gracia-Ramos AE[SUP]1[/SUP].
Author information
Abstract
In the recent coronavirus disease (COVID-19) outbreak, a higher proportion of patients with severe disease were found in older persons with comorbidities. This observation has been related to the use of drugs that can increase the cellular expression of angiotensin-converting enzyme 2 (ACE2) that has been recognized as target to which the virus bind to cells. Although this hypothesis is possible, it may also have other explanations which are discussed.
Copyright ? 2020 IMSS. Published by Elsevier Inc. All rights reserved.
KEYWORDS:
Coronavirus; Coronavirus infections; Diabetes mellitus; Hypertension
PMID:32279908DOI:10.1016/j.arcmed.2020.03.011
Is the ACE2 Overexpression a Risk Factor for COVID-19 Infection?
Gracia-Ramos AE[SUP]1[/SUP].
Author information
Abstract
In the recent coronavirus disease (COVID-19) outbreak, a higher proportion of patients with severe disease were found in older persons with comorbidities. This observation has been related to the use of drugs that can increase the cellular expression of angiotensin-converting enzyme 2 (ACE2) that has been recognized as target to which the virus bind to cells. Although this hypothesis is possible, it may also have other explanations which are discussed.
Copyright ? 2020 IMSS. Published by Elsevier Inc. All rights reserved.
KEYWORDS:
Coronavirus; Coronavirus infections; Diabetes mellitus; Hypertension
PMID:32279908DOI:10.1016/j.arcmed.2020.03.011