tetano
Editor, Senior Moderator
Arch Dis Child
. 2021 Jul 22;archdischild-2021-322062.
doi: 10.1136/archdischild-2021-322062. Online ahead of print.
COVID-19 in children with haematological malignancies
Gerard Cathal Millen[SUP] 1 2 [/SUP], Roland Arnold[SUP] 3 [/SUP], Jean-Baptiste Cazier[SUP] 4 [/SUP], Helen Curley[SUP] 3 [/SUP], Richard Feltbower[SUP] 5 [/SUP], Ashley Gamble[SUP] 6 [/SUP], Adam Glaser[SUP] 5 7 [/SUP], Richard G Grundy[SUP] 6 8 [/SUP], Laura Kirton[SUP] 9 [/SUP], Lennard Y W Lee[SUP] 3 10 [/SUP], Martin G McCabe[SUP] 11 12 [/SUP], Claire Palles[SUP] 3 [/SUP], Bob Phillips[SUP] 13 14 [/SUP], Charles A Stiller[SUP] 12 [/SUP], Csilla Varnai[SUP] 3 4 [/SUP], Pamela Kearns[SUP] 9 2 [/SUP]
Affiliations
Abstract
Background: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies.
Methods: We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded.
Results: Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies.
Interpretation: Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.
Keywords: COVID-19; data collection; epidemiology.
. 2021 Jul 22;archdischild-2021-322062.
doi: 10.1136/archdischild-2021-322062. Online ahead of print.
COVID-19 in children with haematological malignancies
Gerard Cathal Millen[SUP] 1 2 [/SUP], Roland Arnold[SUP] 3 [/SUP], Jean-Baptiste Cazier[SUP] 4 [/SUP], Helen Curley[SUP] 3 [/SUP], Richard Feltbower[SUP] 5 [/SUP], Ashley Gamble[SUP] 6 [/SUP], Adam Glaser[SUP] 5 7 [/SUP], Richard G Grundy[SUP] 6 8 [/SUP], Laura Kirton[SUP] 9 [/SUP], Lennard Y W Lee[SUP] 3 10 [/SUP], Martin G McCabe[SUP] 11 12 [/SUP], Claire Palles[SUP] 3 [/SUP], Bob Phillips[SUP] 13 14 [/SUP], Charles A Stiller[SUP] 12 [/SUP], Csilla Varnai[SUP] 3 4 [/SUP], Pamela Kearns[SUP] 9 2 [/SUP]
Affiliations
- PMID: 34301621
- DOI: 10.1136/archdischild-2021-322062
Abstract
Background: Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies.
Methods: We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded.
Results: Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies.
Interpretation: Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.
Keywords: COVID-19; data collection; epidemiology.