tetano
Editor, Senior Moderator
Arch Clin Neuropsychol
. 2024 Jun 8:acae042.
doi: 10.1093/arclin/acae042. Online ahead of print. Neurocognitive Impairment in Long COVID: A Systematic Review
Eugenia Panagea[SUP] 1 [/SUP], Lambros Messinis[SUP] 1 2 [/SUP], Maria Christina Petri[SUP] 1 [/SUP], Ioannis Liampas[SUP] 3 [/SUP], Emmanouil Anyfantis[SUP] 4 [/SUP], Grigorios Nasios[SUP] 4 [/SUP], Panayiotis Patrikelis[SUP] 1 [/SUP], Mary Kosmidis[SUP] 1 [/SUP]
Affiliations
Objective: Although Coronavirus disease 2019 (COVID-19) is primarily a respiratory infectious disease, it has also been associated with a wide range of other clinical manifestations. It is widely accepted in the scientific community that many patients after recovery continue to experience COVID-19-related symptoms, including cognitive impairment. The aim of this systematic review was to investigate the cognitive profile of patients with long-COVID syndrome.
Methods: A systematic search of empirical studies was conducted through the PubMed/Medline and Scopus electronic databases. Cross-sectional and longitudinal studies published between 2020 and 2023 were included.
Results: Of the 516 studies assessed for eligibility, 36 studies met the inclusion criteria. All included studies support the presence of persistent cognitive changes after COVID-19 disease. Executive function, memory, attention, and processing speed appear to be the cognitive domains that are predominantly associated with long-COVID syndrome, whereas language is an area that has not been sufficiently investigated.
Conclusions: In this review, the high frequency of cognitive impairment after COVID-19 is evident. If we consider that cognitive functioning affects our ability to live independently and is a key determinant of our quality of life, it is imperative to precisely define those factors that may induce cognitive impairment in COVID-19 survivors, with the ultimate goal of early diagnosis of cognitive changes and, consequently, the development of targeted rehabilitation interventions to address them.
Keywords: Language; Long COVID; Neurocognitive impairment.
. 2024 Jun 8:acae042.
doi: 10.1093/arclin/acae042. Online ahead of print. Neurocognitive Impairment in Long COVID: A Systematic Review
Eugenia Panagea[SUP] 1 [/SUP], Lambros Messinis[SUP] 1 2 [/SUP], Maria Christina Petri[SUP] 1 [/SUP], Ioannis Liampas[SUP] 3 [/SUP], Emmanouil Anyfantis[SUP] 4 [/SUP], Grigorios Nasios[SUP] 4 [/SUP], Panayiotis Patrikelis[SUP] 1 [/SUP], Mary Kosmidis[SUP] 1 [/SUP]
Affiliations
- PMID: 38850628
- DOI: 10.1093/arclin/acae042
Objective: Although Coronavirus disease 2019 (COVID-19) is primarily a respiratory infectious disease, it has also been associated with a wide range of other clinical manifestations. It is widely accepted in the scientific community that many patients after recovery continue to experience COVID-19-related symptoms, including cognitive impairment. The aim of this systematic review was to investigate the cognitive profile of patients with long-COVID syndrome.
Methods: A systematic search of empirical studies was conducted through the PubMed/Medline and Scopus electronic databases. Cross-sectional and longitudinal studies published between 2020 and 2023 were included.
Results: Of the 516 studies assessed for eligibility, 36 studies met the inclusion criteria. All included studies support the presence of persistent cognitive changes after COVID-19 disease. Executive function, memory, attention, and processing speed appear to be the cognitive domains that are predominantly associated with long-COVID syndrome, whereas language is an area that has not been sufficiently investigated.
Conclusions: In this review, the high frequency of cognitive impairment after COVID-19 is evident. If we consider that cognitive functioning affects our ability to live independently and is a key determinant of our quality of life, it is imperative to precisely define those factors that may induce cognitive impairment in COVID-19 survivors, with the ultimate goal of early diagnosis of cognitive changes and, consequently, the development of targeted rehabilitation interventions to address them.
Keywords: Language; Long COVID; Neurocognitive impairment.