Antiviral treatment and virological monitoring of oseltamivir-resistant influenza virus A(H1N1)pdm09 in a patient with chronic B lymphocytic leukemia

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J Infect Chemother. 2019 Apr 20. pii: S1341-321X(18)30460-4. doi: 10.1016/j.jiac.2018.11.008. [Epub ahead of print]
[h=1]Antiviral treatment and virological monitoring of oseltamivir-resistant influenza virus A(H1N1)pdm09 in a patient with chronic B lymphocytic leukemia.[/h] Salata C[SUP]1[/SUP], Sgarabotto D[SUP]2[/SUP], Del Vecchio C[SUP]1[/SUP], Solimbergo E[SUP]3[/SUP], Marini G[SUP]2[/SUP], Nicol? S[SUP]2[/SUP], Franchin E[SUP]1[/SUP], Parolin C[SUP]1[/SUP], Calistri A[SUP]3[/SUP], Pal? G[SUP]4[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We report the virological monitoring and the antiviral therapy adopted for the treatment of a patient affected by chronic B lymphocytic leukemia, who experienced a severe pneumonia with long-term shedding of influenza virus A(H1N1)pdm09, characterized by an early development of oseltamivir resistance.
Copyright ? 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.


[h=4]KEYWORDS:[/h] A(H1N1)pdm09; Chronic lymphocytic leukemia; Influenza virus; Oseltamivir resistance; Triple-combination antiviral drug therapy (TCAD); Zanamivir

PMID: 31014561 DOI: 10.1016/j.jiac.2018.11.008







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