tetano
Editor, Senior Moderator
Cytokine. 2019 Dec 31;127:154961. doi: 10.1016/j.cyto.2019.154961. [Epub ahead of print] [h=1]Antiviral responses against chicken respiratory infections: Focus on avian influenza virus and infectious bronchitis virus.[/h]
Barjesteh N[SUP]1[/SUP], O'Dowd K[SUP]2[/SUP], Vahedi SM[SUP]3[/SUP].
[h=3]Author information[/h] 1 Research Group on Infectious Diseases in Production Animals (GREMIP), and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, Universit? de Montr?al, Saint-Hyacinthe, Quebec, Canada. Electronic address: neda.barjesteh@umontreal.ca. 2 Research Group on Infectious Diseases in Production Animals (GREMIP), and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, Universit? de Montr?al, Saint-Hyacinthe, Quebec, Canada. 3 Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
[h=3]Abstract[/h] Some of the respiratory viral infections in chickens pose a significant threat to the poultry industry and public health. In response to viral infections, host innate responses provide the first line of defense against viruses, which often act even before the establishment of the infection. Host cells sense the presence of viral components through germinal encoded pattern recognition receptors (PRRs). The engagement of PRRs with pathogen-associated molecular patterns leads to the induction of pro-inflammatory and interferon productions. Induced antiviral responses play a critical role in the outcome of the infections. In order to improve current strategies for control of viral infections or to advance new strategies aimed against viral infections, a deep understanding of host-virus interaction and induction of antiviral responses is required. In this review, we summarized recent progress in understanding innate antiviral responses in chickens with a focus on the avian influenza virus and infectious bronchitis virus.
Copyright ? 2019 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Antiviral responses; Chickens; Infectious bronchitis virus; Influenza virus
PMID: 31901597 DOI: 10.1016/j.cyto.2019.154961
Barjesteh N[SUP]1[/SUP], O'Dowd K[SUP]2[/SUP], Vahedi SM[SUP]3[/SUP].
[h=3]Author information[/h] 1 Research Group on Infectious Diseases in Production Animals (GREMIP), and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, Universit? de Montr?al, Saint-Hyacinthe, Quebec, Canada. Electronic address: neda.barjesteh@umontreal.ca. 2 Research Group on Infectious Diseases in Production Animals (GREMIP), and Swine and Poultry Infectious Diseases Research Center (CRIPA), Department of Pathology and Microbiology, Faculty of Veterinary Medicine, Universit? de Montr?al, Saint-Hyacinthe, Quebec, Canada. 3 Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
[h=3]Abstract[/h] Some of the respiratory viral infections in chickens pose a significant threat to the poultry industry and public health. In response to viral infections, host innate responses provide the first line of defense against viruses, which often act even before the establishment of the infection. Host cells sense the presence of viral components through germinal encoded pattern recognition receptors (PRRs). The engagement of PRRs with pathogen-associated molecular patterns leads to the induction of pro-inflammatory and interferon productions. Induced antiviral responses play a critical role in the outcome of the infections. In order to improve current strategies for control of viral infections or to advance new strategies aimed against viral infections, a deep understanding of host-virus interaction and induction of antiviral responses is required. In this review, we summarized recent progress in understanding innate antiviral responses in chickens with a focus on the avian influenza virus and infectious bronchitis virus.
Copyright ? 2019 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Antiviral responses; Chickens; Infectious bronchitis virus; Influenza virus
PMID: 31901597 DOI: 10.1016/j.cyto.2019.154961