tetano
Editor, Senior Moderator
Antimicrob Steward Healthc Epidemiol
. 2023 Jan 17;3(1):e14.
doi: 10.1017/ash.2022.361. eCollection 2023.
Healthcare-associated infections (HAIs) during the coronavirus disease 2019 (COVID-19) pandemic: A time-series analysis
John M Sahrmann[SUP] 1 [/SUP], Katelin B Nickel[SUP] 1 [/SUP], Dustin Stwalley[SUP] 1 [/SUP], Erik R Dubberke[SUP] 1 [/SUP], Patrick G Lyons[SUP] 2 [/SUP], Andrew P Michelson[SUP] 2 [/SUP], Kathleen M McMullen[SUP] 3 [/SUP], Sumanth Gandra[SUP] 1 [/SUP], Margaret A Olsen[SUP] 1 [/SUP], Jennie H Kwon[SUP] 1 [/SUP], Jason P Burnham[SUP] 1 [/SUP]
Affiliations
Abstract
Objective: To use interrupted time-series analyses to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on healthcare-associated infections (HAIs). We hypothesized that the pandemic would be associated with higher rates of HAIs after adjustment for confounders.
Design: We conducted a cross-sectional study of HAIs in 3 hospitals in Missouri from January 1, 2017, through August 31, 2020, using interrupted time-series analysis with 2 counterfactual scenarios.
Setting: The study was conducted at 1 large quaternary-care referral hospital and 2 community hospitals.
Participants: All adults ≥18 years of age hospitalized at a study hospital for ≥48 hours were included in the study.
Results: In total, 254,792 admissions for ≥48 hours occurred during the study period. The average age of these patients was 57.6 (±19.0) years, and 141,107 (55.6%) were female. At hospital 1, 78 CLABSIs, 33 CAUTIs, and 88 VAEs were documented during the pandemic period. Hospital 2 had 13 CLABSIs, 6 CAUTIs, and 17 VAEs. Hospital 3 recorded 11 CLABSIs, 8 CAUTIs, and 11 VAEs. Point estimates for hypothetical excess HAIs suggested an increase in all infection types across facilities, except for CLABSIs and CAUTIs at hospital 1 under the "no pandemic" scenario.
Conclusions: The COVID-19 era was associated with increases in CLABSIs, CAUTIs, and VAEs at 3 hospitals in Missouri, with variations in significance by hospital and infection type. Continued vigilance in maintaining optimal infection prevention practices to minimize HAIs is warranted.
. 2023 Jan 17;3(1):e14.
doi: 10.1017/ash.2022.361. eCollection 2023.
Healthcare-associated infections (HAIs) during the coronavirus disease 2019 (COVID-19) pandemic: A time-series analysis
John M Sahrmann[SUP] 1 [/SUP], Katelin B Nickel[SUP] 1 [/SUP], Dustin Stwalley[SUP] 1 [/SUP], Erik R Dubberke[SUP] 1 [/SUP], Patrick G Lyons[SUP] 2 [/SUP], Andrew P Michelson[SUP] 2 [/SUP], Kathleen M McMullen[SUP] 3 [/SUP], Sumanth Gandra[SUP] 1 [/SUP], Margaret A Olsen[SUP] 1 [/SUP], Jennie H Kwon[SUP] 1 [/SUP], Jason P Burnham[SUP] 1 [/SUP]
Affiliations
- PMID: 36714284
- PMCID: PMC9879893
- DOI: 10.1017/ash.2022.361
Abstract
Objective: To use interrupted time-series analyses to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on healthcare-associated infections (HAIs). We hypothesized that the pandemic would be associated with higher rates of HAIs after adjustment for confounders.
Design: We conducted a cross-sectional study of HAIs in 3 hospitals in Missouri from January 1, 2017, through August 31, 2020, using interrupted time-series analysis with 2 counterfactual scenarios.
Setting: The study was conducted at 1 large quaternary-care referral hospital and 2 community hospitals.
Participants: All adults ≥18 years of age hospitalized at a study hospital for ≥48 hours were included in the study.
Results: In total, 254,792 admissions for ≥48 hours occurred during the study period. The average age of these patients was 57.6 (±19.0) years, and 141,107 (55.6%) were female. At hospital 1, 78 CLABSIs, 33 CAUTIs, and 88 VAEs were documented during the pandemic period. Hospital 2 had 13 CLABSIs, 6 CAUTIs, and 17 VAEs. Hospital 3 recorded 11 CLABSIs, 8 CAUTIs, and 11 VAEs. Point estimates for hypothetical excess HAIs suggested an increase in all infection types across facilities, except for CLABSIs and CAUTIs at hospital 1 under the "no pandemic" scenario.
Conclusions: The COVID-19 era was associated with increases in CLABSIs, CAUTIs, and VAEs at 3 hospitals in Missouri, with variations in significance by hospital and infection type. Continued vigilance in maintaining optimal infection prevention practices to minimize HAIs is warranted.