Giuseppe
Emeritus
[Source: Antimicrobial Agents and Chemotherapy, full page: (LINK). Abstract, edited.]
Antimicrobial Susceptibility Pattern and Epidemiology of Female Urinary Tract Infections in Korea (2010?2011)
Dong Sup Lee a, Hyun-Sop Choe a, Sung Jong Lee b, Woong Jin Bae c, Hyeong Jun Cho d, Byung Il Yoon e, Yong-Hyun Cho e, Chang Hee Han f, Hoon Jang g, Su Bum Park h, Won Jin Cho i and Seung-Ju Lee a#
Author Affiliations: Department of Urology, St. Vincent's Hospital, The Catholic University of Korea, College of Medicine, Suwon, Korea<SUP>a </SUP>Department of Obstetrics, St. Vincent's Hospital, The Catholic University of Korea, College of Medicine, Suwon, Korea<SUP>b </SUP>Department of Urology, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea<SUP>c </SUP>Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea<SUP>d </SUP>Department of Urology, Yeouido St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea<SUP>e </SUP>Department of Urology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Uijeongbu, Korea<SUP>f </SUP>Department of Urology, Daejeon St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Daejeon, Korea<SUP>g </SUP>Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan, Korea<SUP>h </SUP>Department of Urology, Chosun University School of Medicine, Gwangju, Korea<SUP>i</SUP>
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ABSTRACT
This study aimed to (1) investigate the antimicrobial susceptibilities of bacteria that cause urinary tract infections in outpatient and inpatient settings and (2) evaluate the risk factors for emerging antimicrobial drug resistance in urinary tract infections (UTIs) in Korea. In total, 3,023 samples without duplication were collected from females between 25 and 65 years old who had been diagnosed with a urinary tract infection. Multicenter patient data were collected using a Web-based electronic system and then evaluated. The isolation rates (%) of Escherichia coli, Klebsiella pneumoniae and Enterococcus faecium in the outpatient setting were 78.1, 4.7 and 1.3, respectively; in the inpatient setting, the isolation rates of these microorganisms were 37.8, 9.9 and 14.8, respectively. The susceptibilities (%) of E. coli to amikacin, amoxicillin-clavulanic acid, cefotaxime, cefoxitin, ciprofloxacin, piperacillin-tazobactam and imipenem in the outpatient setting were 99.4, 79.8, 89.4, 92.8, 69.8, 96.9 and 100.0, respectively; in the inpatient setting, the susceptibilities to these antibiotics were 97.8, 73.9, 73.7, 82.1, 53.6, 93.2 and 100.0, respectively. The most unique and common risk factor for emerging antimicrobial-resistant E. coli, K. pneumoniae and E. faecium was previous exposure to antimicrobials. On the basis of these data, the use of fluoroquinolones should be reserved until culture data are available for the treatment of UTIs in Korea. The present study will serve as a useful reference for far-eastern Asia.
FOOTNOTES
# Correspondence: Seung-Ju Lee, M.D., Ph.D., Department of Urology, St. Vincent's Hospital, The Catholic University of Korea, College of Medicine, 93-6 Ji-dong Paldal-gu, Suwon 442-723, South Korea. TEL: +82-31-249-7470. FAX: +82-31-253-0949. E-mail: lee.seungju@gmail.com
Copyright ? 2013, American Society for Microbiology. All Rights Reserved.
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Antimicrobial Susceptibility Pattern and Epidemiology of Female Urinary Tract Infections in Korea (2010?2011)
Dong Sup Lee a, Hyun-Sop Choe a, Sung Jong Lee b, Woong Jin Bae c, Hyeong Jun Cho d, Byung Il Yoon e, Yong-Hyun Cho e, Chang Hee Han f, Hoon Jang g, Su Bum Park h, Won Jin Cho i and Seung-Ju Lee a#
Author Affiliations: Department of Urology, St. Vincent's Hospital, The Catholic University of Korea, College of Medicine, Suwon, Korea<SUP>a </SUP>Department of Obstetrics, St. Vincent's Hospital, The Catholic University of Korea, College of Medicine, Suwon, Korea<SUP>b </SUP>Department of Urology, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea<SUP>c </SUP>Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea<SUP>d </SUP>Department of Urology, Yeouido St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea<SUP>e </SUP>Department of Urology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Uijeongbu, Korea<SUP>f </SUP>Department of Urology, Daejeon St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Daejeon, Korea<SUP>g </SUP>Department of Internal Medicine, Pusan National University Yangsan Hospital, Pusan, Korea<SUP>h </SUP>Department of Urology, Chosun University School of Medicine, Gwangju, Korea<SUP>i</SUP>
<SUP></SUP>
ABSTRACT
This study aimed to (1) investigate the antimicrobial susceptibilities of bacteria that cause urinary tract infections in outpatient and inpatient settings and (2) evaluate the risk factors for emerging antimicrobial drug resistance in urinary tract infections (UTIs) in Korea. In total, 3,023 samples without duplication were collected from females between 25 and 65 years old who had been diagnosed with a urinary tract infection. Multicenter patient data were collected using a Web-based electronic system and then evaluated. The isolation rates (%) of Escherichia coli, Klebsiella pneumoniae and Enterococcus faecium in the outpatient setting were 78.1, 4.7 and 1.3, respectively; in the inpatient setting, the isolation rates of these microorganisms were 37.8, 9.9 and 14.8, respectively. The susceptibilities (%) of E. coli to amikacin, amoxicillin-clavulanic acid, cefotaxime, cefoxitin, ciprofloxacin, piperacillin-tazobactam and imipenem in the outpatient setting were 99.4, 79.8, 89.4, 92.8, 69.8, 96.9 and 100.0, respectively; in the inpatient setting, the susceptibilities to these antibiotics were 97.8, 73.9, 73.7, 82.1, 53.6, 93.2 and 100.0, respectively. The most unique and common risk factor for emerging antimicrobial-resistant E. coli, K. pneumoniae and E. faecium was previous exposure to antimicrobials. On the basis of these data, the use of fluoroquinolones should be reserved until culture data are available for the treatment of UTIs in Korea. The present study will serve as a useful reference for far-eastern Asia.
FOOTNOTES
# Correspondence: Seung-Ju Lee, M.D., Ph.D., Department of Urology, St. Vincent's Hospital, The Catholic University of Korea, College of Medicine, 93-6 Ji-dong Paldal-gu, Suwon 442-723, South Korea. TEL: +82-31-249-7470. FAX: +82-31-253-0949. E-mail: lee.seungju@gmail.com
Copyright ? 2013, American Society for Microbiology. All Rights Reserved.
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