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Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses

Mary Wilson

Well-known member
July 23, 2021

doi:10.1001/jama.2021.12339

Ilies Benotmane, MD[SUP]1[/SUP]; Gabriela Gautier, MD[SUP]1[/SUP]; Peggy Perrin, MD[SUP]1[/SUP]; et al

Studies have reported low seroconversion rates (58% after the second dose) in solid organ transplant recipients who received a messenger RNA (mRNA) SARS-CoV-2 vaccine.[SUP]1[/SUP][SUP],2[/SUP] Based on this evidence, the French National Authority for Health issued a recommendation in April 2021 to administer a third vaccine dose in immunosuppressed patients who did not respond after 2 doses. We examined the antibody responses of kidney transplant recipients who did not respond to 2 doses and received a third dose (100 μg) of the mRNA-1273 vaccine (Moderna).
...
https://jamanetwork.com/journals/ja...tent=covid_weekly_highlights&utm_medium=email
 
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