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Antibodies against avian-like A (H1N1) swine influenza virus among swine farm residents in eastern China

tetano

Editor, Senior Moderator
J Med Virol. 2014 Apr;86(4):592-6. doi: 10.1002/jmv.23842. Epub 2013 Nov 8.
Antibodies against avian-like A (H1N1) swine influenza virus among swine farm residents in eastern China.
Yin X, Yin X, Rao B, Xie C, Zhang P, Qi X, Wei P, Liu H.
Author information
Abstract

In 2007, the avian-like H1N1 virus (A/swine/Zhejiang/1/07) was first isolated in pigs in China. Recently, it was reported that a 3-year-old boy was infected with avian-like A (H1N1) swine influenza virus (SIV) in Jiangsu Province, China. To investigate the prevalence of avian-like A (H1N1) SIV infection among swine farm residents in eastern China, an active influenza surveillance program was conducted on swine farms in this region from May 21, 2010 through April 22, 2012. A total of 1,162 participants were enrolled, including 1,136 persons from 48 pig farms, as well as 26 pig farm veterinarians. A total of 10.7% and 7.8% swine farm residents were positive for antibodies against avian-like A (H1N1) SIV by HI and NT assay, respectively, using 40 as the cut-off antibody titer. Meanwhile, all the serum samples collected from a control of healthy city residents were negative against avian-like A (H1N1) SIV. As the difference in numbers of antibody positive samples between the swine farm residents and health city residents controls was statistically significant (P = 0.002), these data suggest that occupational exposure to pigs may increase swine farm residents' and veterinarians' risk of avian-like A (H1N1) SIV infection in eastern China. This study provides the first data on avian-like A (H1N1) SIV infections in humans in China; the potential for avian-like A (H1N1) SIV entering the human population should also be taken into consideration. J. Med. Virol. 86:592-596, 2014. ? 2013 Wiley Periodicals, Inc.

? 2013 Wiley Periodicals, Inc.
KEYWORDS:

avian-like A (H1N1), swine farm residents, swine influenza viruses

PMID:
24497077
[PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/24497077
 
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