Re: Japan Reports Tamiflu-Resistant H1N1 Influenza Case
Re: Japan Reports Tamiflu-Resistant H1N1 Influenza Case
Re: Japan Reports Tamiflu-Resistant H1N1 Influenza Case
Oseltamivir in Osaka Press Release (Products: Tamiflu) for the avian flu virus was detected indicating the mutant gene from Osaka ○ resistance, indicating that the H275Y Tamiflu-resistant isolates with a mutated avian flu virus genes were reported on the Summary, as attached, to provide information.
○ The virus, now, WHO, National Institute of Infectious Diseases in collaboration center, is scheduled to be implemented and drug susceptibility testing.
○ In Japan, about 500 nationwide surveillance by the virus are carried out in cooperation with the medical institution where the future for the new influenza virus, and not knowing what is expected from the drug-resistant gene mutation .
○ In addition, gene mutations that are resistant to Tamiflu, the severity of the virus (pathogenic) is a direct influence is not.
Oseltamivir in Osaka (product name: Tamiflu) Description of a new flu virus was detected in a mutant gene be resistant.
○ Description of patients from patients living in Osaka, with the avian flu virus resistant to Tamiflu indicates the gene mutation.
○ If this is to begin on May 15, May 17, concentrated contacts of patients confirmed that the avian flu patients.
○ 5 prophylactic administration of the drug from the Monday 18 days (10 days) were made,
May 24 with a fever on May 28 to contact the Counseling Center, fever, and on May 29 in the diagnosis of avian flu.
Sunday May 29 from 5-day Zanamivir (Product name: Relenza) treated by recovery.
○ The samples were collected from patients in the Osaka Prefectural Institute of Public Health,
After separation of the virus culture, the gene sequence was confirmed, June 18,
Be resistant to Tamiflu H275Y mutant gene was confirmed.
○ In addition, the May 15 analysis has been similar for patients who develop the virus strain, indicating the mutant gene was confirmed Tamiflu resistant.
○ then spread to the surrounding, including the Family is not approved.
○ neuraminidase was carried out by the Osaka Prefectural Institute of Public Health (NA) part of the gene (250bp) and the analysis of mutations in the gene (point mutation）（Ａ/Ｈ１Ｎ１； mutation) which arises, seasonal influenza (A/H1N1;Soviet-type) which is caused by hybridization of the year.
○ 6 Monday 30 of the European Center for Disease Control (ECDC) said, in Denmark, as the avian flu patients contact the rich history of travel abroad, who had prophylactic administration of Tamiflu, the drug administration 5 The tests for flu-like symptoms after day, is found to be infected with avian flu.
Then I check the status of drug-resistant, and has been recognized that drug-resistant mutation.
○ For this case, ECDC will never be shown to isolate the virus-resistant gene mutations full TAMI patients are given Tamiflu, a phenomenon that is observed in the seasonal flu, Tamiflu will be resistant For influenza virus, has not been confirmed to be infected by the surrounding public health risk and are not considered.
※ In addition, ECDC's report, in Japan, found that children infected with seasonal flu are being treated by a full TAMI, the 16
The virus was separated from the TAMI shows the percent of full immunity, the infection is introduced, studies that were low.
Oseltamivir in Osaka (product name: Tamiflu) Description of a new flu virus was detected in a mutant gene be resistant.
<!--Yahoo!-->
<!--delicious-->
<!--ライブドア-->
<!--Buzzurl-->